Week 8 - Inflammation Flashcards
What is inflammation? (3)
- an immunologic defense against tissue injury, infection or allergy
- the body’s reaction to injury, irritation, or infection characterized by redness, swelling, warmth, and/or pain
- caused by accumulation of immune cells and substances around the injury or infection
What does inflammation initiate?
- protective process initiated to minimize or remove the pathologic agent or stimulus triggering the inflammation, and to promote healing
What is the correlation between inflammation and infection?
- inflammation is always present with infection, BUT it can also occur in the absence of infection
so inflammation is the first part of infection, but we will not always get infection with inflammation
What is an example of an active acute inflammation?
- sprained ankle (W/I next couple of hours)
What is an example of an active chronic inflammation? (2)
- autoimmune diseases (MS, Lupus)
- long standing, long periods of time
What is an example of active repair/restorative inflammation?
- you broke your arm so now your body is repairing and restoring it
What is local inflammation?
- one area
ie. wrist
What is a systemic inflammation?
all over
What is an example of:
a) Chronic local inflammation
b) acute systemic
c) chronic systemic
a) tuberculosis
b) infectious process
c) entire body infected by autoimmune disease
What are the triggers of inflammation? (4)
- Mechanical trauma
- Thermal, electrical, or chemical injury
- radiation damage
- Biological assault (infections) ie. bacterial, viral
What is the goal for the normal inflammatory response? (2)
- restore normal function of cells
- Fibrous repairs when cells cannot be restored
What is the function of WBC?
- WBC and chemicals serve to protect the body from invaders or cellular/tissue damage
scarring occurs if you cannot regenerate those cells
Types of WBC diagram
What are the 2 types of WBC?
- granulocytes
- Agranulocytes
What are the 3 types of granulocytes?
- Neutrophils
- Eosinophils
- Basophils
