Week 5 - Diuretics + ADH Flashcards
Furosemide and spironolactone effect on kidneys digram
What type of diuretic is furosemide?
- loop diuretic
What is the MOA of furosemide?
Inhibits sodium potassium pump in ascending loop of Henle, recreasing reabsorption of sodium and water
What are the indications of furosemide? (2)
- edema
- hypertension
What are the contraindications of furosemide? (2)
- electrolyte imbalances
- hypovolemia
What are the side effects of furosemide? (3)
- hypotension
- hypokalemia
- tinnitus
What type of diuretic is spironolactone?
- potassium sparing diuretics
What is the MOA of spironolactone
- inhibition of water and sodium reabsorption in the kidney while saving potassium
What are the indications of spironolactone (2)
- like furosemide, however counteract potassium loss
- may be used with furosemide
What are the contraindications of spironolactone? (2)
- hyperkalemia
- hypovolemia
What are the side effects of spironolactone? (2)
- hyperkalemia
- hypotension
What are the diuretic nursing considerations? (5)
- monitor BP
- weights
- urine output
- labs
- Have you followed up with the reason why you gave it in the first place?? Evaluation after administration
Lab values question
Think: what would you administer for high potassium?
What occurs in the hypothalamus-pituitary gland regulation of water? (3)
- Hypothalamic osmoreceptors sense increased osmolality (too many particles, not enough fluid)
- Thirst triggered (decreased in older adult)
- ADH released from pituitary gland in kidney
- free water absorption (not Na)
What can happen with ADH dysfunction? (2)
- syndrome of inappropriate ADH (SIADH)
- diabetes insipidus
