VANCOMYCIN Flashcards
1
Q
Drug class
A
glycopeptides
2
Q
How does it work?
A
inhibits the synthesis of the cell wall of GRAM POSITIVE BACTERIA
3
Q
Indications (2)
A
- gram positive infections
- antibiotic associated colitis
4
Q
What is an example of a gram positive infection?
A
endocarditis
5
Q
What is an example of antibiotic associated colitis?
A
c.difficile
6
Q
Contraindications (2)
A
DOSE REDUCTION IN:
- renal impairment
- elderly
7
Q
Side effects (6)
A
- thrombophlebitis
- Red man syndrome
- hypersensitivity reaction
- nephrotoxicity
- ototoxicity
- blood disorders - thrombocytopenia and neutropenia
8
Q
What is Red man syndrome?
A
severe anaphylactic reaction
9
Q
What happens in ototoxicity side effects? (2)
A
- tinnitus
- hearing loss
10
Q
Interactions (3)
A
CAUSES NEPHROTOXICITY OR OTOTOXICITY
- aminoglycosides
- loop diuretics
- ciclosporin
11
Q
What is ciclosporin?
A
immunosuppressant
12
Q
elimination
A
urine
