CARBIMAZOLE

Question 1

Drug class

Answer 1

anti-thyroid drugs

Question 2

How does it work? (2)

Answer 2

1. reduces the amount of thyroid hormones produced in the thyroid gland
2. it prevents the conversion of iodine to it’s useable form

Question 3

Indications

Answer 3

1. hyperthyroidism

Question 4

Contra-indications (4) (1P and 3Hs)

Answer 4

1. pregnancy
2. hypersensitivity
3. hepatic problems
4. haematological conditions

Question 5

Side effects (6)

Answer 5

1. GI

• nausea
• vomitting
• abdo pain
• constipation
• diarrhoea

2. flu-like symptoms

• headache
• fever
• pain in joints
• general feeling of being unwell

3. skin and hair

• hair loss
• itching
• rashes

4. muscle
   - myopathy - muscle disorders
5. blood cells
   - decreased
6. liver

• inflammation
• yellowing of skin and eyes

Question 6

Interactions (3)

Answer 6

1. digoxin
2. theophylline
3. warfarin

Question 7

elimination

Answer 7

urine