SALBUTAMOL Flashcards

1
Q

Drug class

A

beta-2 agonist

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2
Q

How does it work? (3)

A
  1. beta-2 receptors are found in the smooth muscle of the bronchi, GI tract, uterus and blood vessels
  2. G proteins are stimulated which leads to smooth muscle relaxation
  3. it is short acting
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3
Q

Indications

A
  1. asthma
  2. copd
  3. hyperkaelemia
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4
Q

How does salbutamol work in hyperkaelemia? (2)

A
  1. stimulates Na/K ATPase pump

2. shifts K+ from extra cellar to intracellular component

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5
Q

Contra-indications

A
  1. CVD - cause angina or arrhythmias
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6
Q

Side effects (4)

A
  1. tachycardia
  2. palpitations
  3. anxiety
  4. tremor
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7
Q

Interactions (3)

A
  1. beta-blockers - reduces effectiveness
  2. theophyllline - hyopkaelemia - monitor
  3. corticosteroids - hypokaelmia - monitor
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8
Q

Elimination

A

urine

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