ENOXAPARIN Flashcards

1
Q

Drug class

A

LMWH - heparin

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2
Q

How does it work? (2)

A
  1. inhibits the function of factor Xa and thrombin

2. this prevents the formation of the fibrin clot

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3
Q

Indications (2)

A
  1. vessels
    - venous thrombus embolism (VTE)
  2. heart
    - ACS
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4
Q

Contra-indications (6)

A
  1. clotting
  • clotting disorders
  • anti-coagulants
  1. surgery and invasive procedure
  • spinal anaesthesia
  • lumbar puncture
  1. trauma
  2. renal impairment
    - use lower dose
  3. severe uncontrolled hypertension
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5
Q

Side effects (3)

A
  1. bleeding
  2. injection site reactions
  3. thrombocytopenia
    - induced by heparin
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6
Q

Interactions (2)

A
  1. anti-thrombotic drugs
  2. anti-platelets drugs

increases risk of bleeding

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7
Q

Elimination

A

kidneys

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