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YEAR 3 DRUGS > LAMOTRIGINE > Flashcards

LAMOTRIGINE Flashcards

1
Q

Drug class

A

anti-convulsant

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2
Q

How does it work? (3)

A
  1. enhances GABA
    - this is an inhibitory neurotransmitter
  2. reduces transmission of pain
  3. inhibits voltage gated sodium channels
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3
Q

Indications (2)

A
  1. epilepsy

2. bipolar

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4
Q

Contra-indications (3)

A
  1. hormones
  2. pregnancy
  3. breast-feeding
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5
Q

Side effects (4)

A
  1. life threatening skin reactions
    - Steven-Johnson’s syndrome
  2. Rash, fever and fatigue
  3. loss of balance and vision
  4. sleep
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6
Q

Interactions

A
  1. drugs metabolised by cytochrome P450 enzymes
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7
Q

Elimination

A

urine

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YEAR 3 DRUGS (65 decks)

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