CARBOCYSTEINE

Question 1

Drug class

Answer 1

Mucolytics

Question 2

How does it work? (4)

Answer 2

1. it reduces the viscosity of the sputum
2. it dissolves the thick mucus

3.It does this by:

• dissolving chemical bonds
• altering mucin containing components

Question 3

Indications (2)

Answer 3

1. COPD

2. Bronchiectasis

Question 4

Contra-indications (2)

Answer 4

1. peptic ulcers

2. pregnancy

Question 5

Side effects (3)

Answer 5

1. Steven’s Johnson syndrome
2. Erythema multiforme

RARE

3. GI bleed

Question 6

What is Steven’s Johnson syndrome? (2)

Answer 6

• a life-threatening skin condition, in which cell death causes the epidermis to separate from the dermis.
• thought to be a hypersensitivity complex that affects the skin and the mucous membranes.

Question 7

What is erythema multiforme? (2)

Answer 7

• a hypersensitivity reaction usually triggered by infections, most commonly herpes simplex virus (HSV).
• It presents with a skin eruption characterised by a typical target lesion.

Question 8

Interactions

Answer 8

none

Question 9

Elimination

Answer 9

urine