Urinalysis Flashcards

1
Q

Serum creatinine and BUN rise after glomerular filtration rate falls below __________.

A

40 ml/min

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2
Q

Why is creatinine a good indicator of GFR?

A

Because it is not reabsorbed (mostly)
It is not bound to plasma proteins
It is only partially secreted by the peritubular capillaries

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3
Q

Urine must be analyzed within _____ hours to be accurate.

A

two (if you need to wait longer than two hours, then the sample must be refrigerated)

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4
Q

Polyuria is roughly defined as ____________.

A

greater than 2 liters of urine in 24 hours

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5
Q

For urine cultures, incubation must be done for longer if the patient ___________.

A

is receiving antibiotics

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6
Q

What are 24-hour samples used for?

A

Hormone detection, protein electrophoresis, and electrolyte analysis

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7
Q

Anuria is defined as less than __________.

A

100 ml of urine over 24 hours

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8
Q

List the colors of some common urine abnormalities.

A

Bile: yellow/green/brown
Urobilinogen: orange/red/brown
Blood and hemoglobin: red/pink
Methemoglobin, L-dopa, rhabdomyolysis: black

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9
Q

Reagent strips must be ____________.

A

kept in a cool, dry space with a tight lid

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10
Q

Reagent strips should be placed into urine for no longer than ________.

A

one second

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11
Q

Alkaline urine is a hallmark of __________.

A

renal tubular acidosis

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12
Q

Normally, there is less than _______ grams of protein in a day’s worth of urine.

A

0.5

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13
Q

What are some patient characteristics that might increase protein content in the urine?

A

Age (i.e., the elderly)
Posture (standing makes you have more protein in the urine)
Nephrotic syndrome
Multiple myeloma

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14
Q

What two proteins account for most of the urinary protein?

A

Albumin and Tamm-Horsfall

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15
Q

Proteinuria is defined as __________.

A

greater than 150 mg/dl

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16
Q

Glucose is normally _________ in urine.

A

undetectable

17
Q

Four conditions can lead to glucose in the urine. What are they?

A

Diabetes, endocrine disorders, pregnancy, and pancreatic disorders

18
Q

__________ are indicative of Gram-negative bacteria in the urine.

A

Nitrites

19
Q

Even refrigerated urine samples cannot be analyzed after ________.

A

24 hours

20
Q

Oliguria is defined as __________.

A

less than 500 ml of urine in 24 hours

21
Q

Do not spin urine samples for ________ testing.

A

dipstick

22
Q

High specific gravity in a patient with oliguria indicates ____________.

A

a pre-renal disorder

23
Q

What would the urine pH be in metabolic or respiratory acidosis?

A

low

24
Q

What organism can cause markedly high pH in a UTI?

A

Proteus

25
Q

We normally excrete less than ______ grams of protein per day.

A

0.5

26
Q

On the +1 to +4 scale, what is proteinuria?

A

At least +3 (+3 is 200 mg/dl, and you need greater than 150 mg/dl to qualify as having proteinuria)

27
Q

The dipstick glucose tests only detect _________.

A

glucose–no other forms of sugar will be detected

28
Q

If microscopy reveals no RBCs, but the sample tests positive for blood, what is the conclusion?

A

Presence of hemoglobin!

29
Q

Free RBCs indicate _____________.

A

post-renal injury

30
Q

___________ is an indicator of neutrophils in the urine.

A

Leukocyte esterase

31
Q

What can you collect in centrifuged samples?

A
CCCO
Cells
Casts
Crystals
Organisms
32
Q

Having a few hyaline casts is normal, but more indicate ______________.

A

dehydration, fever, or renal injury

33
Q

Matrix casts are indicative of ___________.

A

chronic renal failure

34
Q

Uric acid crystals are nonspecific, but increased numbers suggest _____________.

A

increased cell turnover (such as in chemotherapy) or Lesch-Nyhan disease

35
Q

Dysmorphic RBCs indicate _________ origin.

A

glomerular

36
Q

The __________ void is the preferred for analysis.

A

first morning

37
Q

What else (other than DKA) can cause ketones in the urine?

A

Alcoholism
Cirrhosis
Fasting
Prolonged exercise