Overview of the Pulmonary System/Lung Development Flashcards

1
Q

Lungs are the only organ in mammals that can participate in ___________.

A

gas exchange

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2
Q

The lungs are the only organ that constantly surveys _____________.

A

the inside of the body (100% of cardiac output) and the outside of the body

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3
Q

The airway branches about 23 times. Gas exchange does not occur in the first _______ branch points.

A

16

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4
Q

There are two types of pneumocytes: ____________.

A

type I (simple squamous epithelium) and type II (secretory)

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5
Q

Differentiate ventilation and respiration.

A

Ventilation is the movement of air into and out of the lungs, while respiration is gas exchange.

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6
Q

The lungs develop from the embryonic ________.

A

endoderm

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7
Q

The lung buds develop ventrally into the mesoderm at week ________.

A

four

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8
Q

The lung buds develop from buds between the _____________.

A

4th and 6th branchial (aka pharyngeal) arches

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9
Q

At week _______, lung development is halted by impeding on the liver.

A

seven

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10
Q

When does the embryonic stage take place?

A

4-7 weeks

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11
Q

When does the pseudoglandular stage take place?

A

7-16 weeks

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12
Q

When does the canalicular stage take place?

A

17-26 weeks

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13
Q

What epithelium differentiates in the pseudoglandular stage?

A

Conducting airway epithelium

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14
Q

_____ percent of true alveoli don’t appear until after birth.

A

Ninety

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15
Q

The lungs bud off of the __________.

A

primitive foregut

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16
Q

Type II pneumocytes appear at the end of ___________.

A

month six

17
Q

What is the postnatal stage called?

A

Alveolar stage

18
Q

When does the first bronchial branching occur?

A

Around day 28

19
Q

The branching pattern is determined by __________.

A

the mesoderm

20
Q

Branching occurs by ____________.

A

collagen deposition in the forking of the branch

21
Q

The canalicular stage is characterized by formation of the __________.

A

bronchioles and capillary bed

22
Q

The saccular stage takes place from __________.

A

26 weeks to birth

23
Q

What happens in lung development after birth?

A

The capillary network lengthens.

24
Q

Respiratory bronchioles subdivide to produce terminal sacs in the _________.

A

saccular stage

25
Q

The bronchus is lined with _________ epithelium, while the bronchioles are lined with ___________ epithelium.

A

ciliated pseudostratified columnar; simple

26
Q

Gas exchange takes place distal to the ___________.

A

terminal bronchioles

27
Q

In addition to secreting surfactant, type II cells also __________.

A

repair type I cells