Integrated CV Pharmacology Review

Question 1

The most effective lipid-lowering agents work by ____________.

Answer 1

increasing LDL receptors on hepatocytes

Question 2

What are contraindications of fibrinolytic therapy?

Answer 2

Recent surgery, recent stroke, bleeding disorders, and active peptic ulcer disease

Question 3

Remember that unstable angina and NSTEMI will often have _______ in addition to ST-segment depression.

Answer 3

T wave inversion

Question 4

NSTEMI and unstable angina should only be catheterized if ____________.

Answer 4

risk assessment is high or pain recurs

Question 5

The three anti-ischemic drugs are _________.

Answer 5

ß-blockers, nitrates, and calcium-channel blockers

Question 6

_______ is the most fibrin-specific lytic agent, while ________ is the least.

Answer 6

Tenecteplase; streptokinase

Question 7

_______ are usually not given in primary prevention of ACS.

Answer 7

Anticoagulant drugs

Question 8

Once again, list some GIIb/IIIa inhibitors.

Answer 8

Abciximab, tirofiban, and eptifibatide

Question 9

What are the four categories of people who benefit from statins?

Answer 9

Those with LDLs > 190; diabetics; individuals with known ASCVD; and people older than 40 with 10-year risks > 7.5%

Question 10

Statins are pregnancy category ___.

Answer 10

X

Question 11

________ require brief drug holidays in order to avoid tolerance.

Answer 11

Nitrates

Question 12

____ selective ß-blockers have fewer pulmonary side effects.

Answer 12

ß1