Test 92 Flashcards
segmental demyleination and endoneural inflammatroy infiltrate
GBS
WErdnig Hoffman syndrome
anterior horn cell damage
floppy child syndrome
degeneration of dorsal columns and lateral cerebrospinal tracts
loss of position and vibration sense, spastic paresis, ataxia
B12 def> subactue, combined myelopathy
neonatal intraventricular hemorrhage
occurs in the fragile GERMINAL MATRIX and increaeses in frequency w/ decreasing age/birth weight
rupture of cortical bridging veins
subdural hematoma
MMA and head trauma
epidural hematoma
saccular berry aneurysm
subarachnoid hemorrhage
assoc. EDS
ivnasive aspergillosis
immunosuppressed patients
thin septatate hyphae w/ acute V shaped braniching
proonged neutropenia is assoc. w/ leukemia/lymphoma tx is a RF
Small intestine mucosa containing enlarged, foamy mphages packed w/ both rod shpaed bacilli and PAS positive, diastase resistant granules
Middle aged male
Malabsoprtion, diarrhea, weight loss
TRopheryma Whipelli
destruction of interlobular bile ducts by granulomatous inflammationa nd heavy portal tract infiltrate of mphages, lymphocytes, plasma cells, eosinophils
PBC
chronic liver disease d/t autoimmune destruction of intrahepatic bile ducts and cholestasis
middle aged female w/ fever and prolonged episode of severe right upper abodminal pain after mfatty meal
acute cholecystitis
male w/ fatigue, high alk phos and hx of UC
primary sclerosing cholangitis
older F w/ weight loss, abomdinal discomfort, jaundice, epigastric mass
pancreatic cancer
MC GI malignancy
colon adenocarinoma
location of colon adenocarcinoma
REctosigmoid colon> pts have obstructing sxs
Ascending colon
CRC> right sided, large, bulky masses that protrude into colonic lumen
More likely to bleed!!
Colon adenocarcinomas assoc w/ HNPCC
multiple sites
Painless LN enlargement, waking and waning lymphatdenopathy, or abdominal discomfort from an abodminal mass
follicular lylmphoma
B cell origin, t(14;18), overexpression of bcl-2 oncogene
MC indolent NH lymphoma in adults
large LN or extra nodal mass
Waldeyer ring (oropharyngeal ympohoid tissue)
TI tract involvement
Diffuse large cell lymphoma
Acute lymphoblastic leukemia
MC in CHILDREN
lymphadenopathy hepatosplenomegaly fever bleeding bone pain
pre B and T lymphoblasts
Splenomegaly and pancytopenia in older men
positive for TRAP
Hairy cell leukemia
hypOphosphorylated RB
ACTIVE
prevents damaged cells forom preceeding past G1 to S checkpoint
phospohorylated RB
INACTIVE
allows damaged cells to enter mitosis
main inducer of apoptosis
p53 (policeman)
phosphodiesterase inhibitors
increased cAMP> increased intracellular Ca in cardiac myocytes> vasodilation
increased cardiac contractility
most important steps for prevention of CVC infections
proprer hand washing full barrier precuations during insertion of central line chlorhexidine for skin disinfection avoidance of femoral insertion site remove catheter when no longer needed
decreased GFR
hyperkalemia
cough
angioedema
Common SE of ACE
calcific deposits in musuclar arteries in people older than 50
monkebergs medial calcific sclerosis (medial calcinosis)
clinicall asymptomatic
transmural inflammation of arterial wall w/ fibrinoid necrosis
polyarteriis nodosa
MC benign lung tumor
Coin lesion in pt 50-60
composed of disorganized CARTILAGE, fibrous and adipose tissue
Hamartomas
keratin pearls
Sq CC
alveolar grwoth pattern w/out invasion
arises at lung periphery and distributes along alveolar septae w/ out ascular/stromal invasion
bronchioalveolar carcinoma
exertional dyspnea and difficulty sleeping
LV failure
swollen LN
red eyes
high fevers
strawberry tongue
Kawasaki disease
