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Step 1 > Test 92 > Flashcards

Test 92 Flashcards

1
Q

segmental demyleination and endoneural inflammatroy infiltrate

A

GBS

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2
Q

WErdnig Hoffman syndrome

A

anterior horn cell damage

floppy child syndrome

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3
Q

degeneration of dorsal columns and lateral cerebrospinal tracts

loss of position and vibration sense, spastic paresis, ataxia

A

B12 def> subactue, combined myelopathy

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4
Q

neonatal intraventricular hemorrhage

A

occurs in the fragile GERMINAL MATRIX and increaeses in frequency w/ decreasing age/birth weight

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5
Q

rupture of cortical bridging veins

A

subdural hematoma

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6
Q

MMA and head trauma

A

epidural hematoma

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7
Q

saccular berry aneurysm

A

subarachnoid hemorrhage

assoc. EDS

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8
Q

ivnasive aspergillosis

A

immunosuppressed patients

thin septatate hyphae w/ acute V shaped braniching

proonged neutropenia is assoc. w/ leukemia/lymphoma tx is a RF

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9
Q

Small intestine mucosa containing enlarged, foamy mphages packed w/ both rod shpaed bacilli and PAS positive, diastase resistant granules

Middle aged male

Malabsoprtion, diarrhea, weight loss

A

TRopheryma Whipelli

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10
Q

destruction of interlobular bile ducts by granulomatous inflammationa nd heavy portal tract infiltrate of mphages, lymphocytes, plasma cells, eosinophils

A

PBC

chronic liver disease d/t autoimmune destruction of intrahepatic bile ducts and cholestasis

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11
Q

middle aged female w/ fever and prolonged episode of severe right upper abodminal pain after mfatty meal

A

acute cholecystitis

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12
Q

male w/ fatigue, high alk phos and hx of UC

A

primary sclerosing cholangitis

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13
Q

older F w/ weight loss, abomdinal discomfort, jaundice, epigastric mass

A

pancreatic cancer

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14
Q

MC GI malignancy

A

colon adenocarinoma

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15
Q

location of colon adenocarcinoma

A

REctosigmoid colon> pts have obstructing sxs

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16
Q

Ascending colon

A

CRC> right sided, large, bulky masses that protrude into colonic lumen

More likely to bleed!!

17
Q

Colon adenocarcinomas assoc w/ HNPCC

A

multiple sites

18
Q

Painless LN enlargement, waking and waning lymphatdenopathy, or abdominal discomfort from an abodminal mass

A

follicular lylmphoma

B cell origin, t(14;18), overexpression of bcl-2 oncogene

MC indolent NH lymphoma in adults

19
Q

large LN or extra nodal mass

Waldeyer ring (oropharyngeal ympohoid tissue)

TI tract involvement

A

Diffuse large cell lymphoma

20
Q

Acute lymphoblastic leukemia

A

MC in CHILDREN

lymphadenopathy
hepatosplenomegaly
fever
bleeding
bone pain

pre B and T lymphoblasts

21
Q

Splenomegaly and pancytopenia in older men

positive for TRAP

A

Hairy cell leukemia

22
Q

hypOphosphorylated RB

A

ACTIVE

prevents damaged cells forom preceeding past G1 to S checkpoint

23
Q

phospohorylated RB

A

INACTIVE

allows damaged cells to enter mitosis

24
Q

main inducer of apoptosis

A

p53 (policeman)

25
Q

phosphodiesterase inhibitors

A

increased cAMP> increased intracellular Ca in cardiac myocytes> vasodilation

increased cardiac contractility

26
Q

most important steps for prevention of CVC infections

A 
proprer hand washing
full barrier precuations during insertion of central line
chlorhexidine for skin disinfection
avoidance of femoral insertion site
remove catheter when no longer needed
27
Q

decreased GFR
hyperkalemia
cough
angioedema

A

Common SE of ACE

28
Q

calcific deposits in musuclar arteries in people older than 50

A

monkebergs medial calcific sclerosis (medial calcinosis)

clinicall asymptomatic

29
Q

transmural inflammation of arterial wall w/ fibrinoid necrosis

A

polyarteriis nodosa

30
Q

MC benign lung tumor

Coin lesion in pt 50-60

composed of disorganized CARTILAGE, fibrous and adipose tissue

A

Hamartomas

31
Q

keratin pearls

A

Sq CC

32
Q

alveolar grwoth pattern w/out invasion

arises at lung periphery and distributes along alveolar septae w/ out ascular/stromal invasion

A

bronchioalveolar carcinoma

33
Q

exertional dyspnea and difficulty sleeping

A

LV failure

34
Q

swollen LN
red eyes
high fevers
strawberry tongue

A

Kawasaki disease

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