Test 63 Flashcards
retinal neovascularization d/t increased VEGF levels
Wet age related macular degeneration
ACUTE vision loss
metamorphosia (distorition o fstraight lines) w/ funduscopy showin gray-green subretinal membrane/subretinal hemorrhage
Wet age reatled macular degeneration
Tx for wet age related mac degeneration
smoking cessation
VEGF inhibitor therapy
*ranibizumba
bevacizumab
drusen deposits
gradual vision loss
Dry AMD
CCR5
+CDR4 bind to HIV gp120
coreceptor that enables HIV to enter cells
*deletion of both genes that code for receptor> resistance to HIV infection
vulnerable to injury around the neck of the fibula
common peroneal nerve
weakness of dorsiflexion
weakness of eversion
loss of sensation over dorsum of foot
deep peroneal
superficial peroneal
inversion
plkantarflexion
tibial nerve
intermittent respiratory sxs in pt w/ normal CSR, occasional sputum eosinophils, reduced FEV1
asthma
*often provoked by inahled allergens like pet dander
Cold air asthma
asthma attacks in pts w/ exercise induced asthma
B2 agonists
abuterol
used to tx asthma
transmissoin HAV
F-O route
overcrowding
poor sanitation
contaminated, water, food, RAW STEAMED SHELLFISH
hemolytic anemia
hypercoagulability
pancytopenia
Paroxysmal nocturnal hemoglobinuria
*PIGA gene that leads to absecne of CD55 and cD59 complement inhibitor proteins (lysis of RBCS)
cancers in DS
ALL
AML
BOTH ACUTE
Cardiact tissue conduction velocity
Park At VENTura AVenude
FASTEST: purkingje> atrial> ventricular> AV node
VIPomas
non beta cell pancreatic islet cell tumor that hypersecrete VIP
VIP increases intestinal Cl loss into stool> excess loss of water, Na, K
also inhibits acid secretion
“pancreatic cholera”
WDHA syndrome (watery diarrhea, hypokalemia, achlorhydria)
TX VIP
Somatosatatin
VIP
relaxation GI SM
inhibits H secretion
stimulates pancreatic bicarb/Cl secretion
infection that causes inflammatory gastroenteritis that can be acquired from domestic animals contaminated foods
Campylobacter infection
esophageal varices
left gastric vein> esophageal vein
hemorrhoids
superior rectal vein> middle and inferior rectal veins
Caput medusae
paraumbilical veins>
superficiala nd inferior epigastric veins
AD condition that results from RBC cytoskeleton abnormalities (spectrin and ankyrin defects)
dx test?
positive osmotic fragility test
hereditary spherocytosis
blocks GPiib/IIa receptor
Abciximab
Glanzmann thrombasthenia
defective/deficient GPIIb/IIIa
attrition bias (form of selection bias)
loss to follow up occurs disproporstionately bewteen exposed and unexposed groups
would lead to a steep decline in worldwide incidence of hepatocellular carcinoma
vaccination agnst HBV
single most impt RF for development of intimal tears> aortic dissection
HYTN
RF for aortic aneurysm
smoking
diabetes
hypercholesterolemia
MAJOR RFs for atherosclerosis
milky plasma that forms a creamy appearing supernatant
low plasma lipoprotein lipase activity
familial chylomicronemia syndrome
prsents in childhood w/ recurrent episodes of ACUTE PANCREATITIS
ABDOMINAL PAIN
familial chylomicronemia syndrome
Apo-C II
organanophosphates act on what receptors
muscarinic and nicotinic
reverses muscarinic effects but NOT nicotinic effects like muscle paralysis
atropine
only medication that reverses both muscarinic and nicotinic effects of orgs
pralidoxime
restores cholinesterase
follow up for moderately elevated alk phos of unclear eatiology
y glutamyl transpeptidase
assess liver functionality
PTT
bilirubin
ablumin
cholesterol
assess structural integrit/cellular intactness of the liver
transaminases
assess biliary tract
alk phos
y glutamyl transferase (used to determine hepatic or bony orgigin)
chronic alcoholism
megaloblastic anemia that develops d/t decreased synthesis of purines and thymidine>
macrocytosis
ovalocytosis
neutrophils/ HYPERSEGMENTED nuclei
folate def
not common in alcoholics
B12 def
nephrotic syndrome in kids 2-8
w/ normal renal fxn
pathognomonic finding
diffuse effacement of foot processes of podocytes found on EM
LM shows NORMAL glomeruli and IF fails to reveal anything
tx for MCD
rapid response to corticosteroids!
depolarizing NMJ blocker that is agumented by this drug during phase I but REVERSED during phase II
Neostigmine