Test 24- HRM Flashcards
hCG has a similar structure to what hormone
TSH
29 y/o M w/ painless scrotal mass
Sweat and heat intolerance
Enlarged non tender right testicle
Increased T3 and T4
Testicular malignancy
tumor associated w/ high hCG concentrations that can stimulate TSH receptors causing hyperthyroidism
Testicular germ cell tumors
responsible for GONADAL differentiation into testes containing sertoli and leydig cells
SRY gene on Y chromosome
cells that produce MIF that prevents devo of female INTERNAL genitalia
Sertoli
Secrete testosterone necessary for devo of male INTERNAL genitalia
Leydig
46 XY genotype fetus has testes w/ normally functioning ley dig cells but total absence of sertoli. What phenoytypes will develop?
No sertoli–> no MIF–> Female internal genitalia
Leydig> testosterone> male internal genitalia> DHT> male external genitalia
Small and underdeveloped ovaries on gross examination. Light microscopy shows ovaries composed of CT with NO follicles
Streak Ovaries
Turner syndrome
Common cardiac comorbidity associated w/ Turners
Bicuspid aortic valve
Replacement of vaginal squamous epithelium with glandualr COLUMNAR epithelium
Vaginal adenosis
Female children of women exposed to DES during pregnancy
XX female with normal ovaries and secondary sex characteristics, presents with amenorrhea and short vagina and variable (rudimentary) uterine devleopment
Vaginal agenesis (Mullerian aplasia)
Cellular myxoid stroma that encircles and sometimes compresses epithelium lined glandular and cystic spaces
Fibroadenomas
MC benign tumor of hte breast that arises in young women in their 20s-30s
fibroadenoma (can increase in size during luteal faze)
New onset genital vesicular rash with a positive Tzank smear in previously asymptomatic pt
Genital herpes HSV2
what drug can reduce recurrences of genital herpes through DAILY treatment
valcyclovir