Test 40 Flashcards
mucopurulent cervicitis w/ cervical motiontenderness is indicator of PID
caused by N/C
can lead to ectopic preg/infertility
dysfunctional uterine bleeding and elevated estrogen
endometrial hyperplasia
vaginal bleeding and fundal size greater than dates
hydatiform mole
diarrhea caused by celiacs can lead to
vit D def
Vit D def
low Ca
increased PTH
decreased phosphorus
*neither Ca of PO4 can be absorbed
bone pain
muscle weakness
NPV
probability of beig free of a disease if test is negative
small circular DNA molecules that resemble bacterial chromomsome
code for proteins
tRNA
rRNA
Mitochondria
reverse T3
ianctive form of thyroid hormone generated from peripheral conversion of T4
Turners inheritance
complete/partial loss of X chrom
paternal meiotic nondisjunction
short stature in turners
missing SHOX gene>
short stature
hypogonadism
anosmia
delayed puberty
kallmann syndrome
absence of GnRH secretory neurons in hypothalamus d/t defective migration from olfactory polacode
medullary carcinoma of the thyroid
pheochromocytoma
oral/intestinal mucosal neuromas
marfinoid habitus
men 2B
neuoromas
small flesh colored nodules on lips and tongue
somatostatin
decreases gastrin secretion
decreases pancreatic fluid secretion
decreasess gall bladder contraction
decreaes insulin/glucagon reelase
responsible for biliary stones in pts w/ somatostatinoma
reduced GB contraction
scrotum lacking palpable testes and bilateral inguinal masses
secodnary sex characteristics well developed
no impairment in sex drive
low sperm count
cryptochordism
atrophic STs (sertoli cells)> decreased sperm count/inhibin levels
leydig cells not impaired> secondary sex normal
cryptorchidism
primary amenorrhea
secondary sex characteristics>
imperforate hymen or MD abnormality
cyclic abdominalk pain, hematocolpos (vagina fills w/ blood)
imperforate hymen
hypersecreting adrenal tumor w/ functionality of outer layer
increased aldosterone (Conn syndrome)
increased Na, decreased K
Paresthesia and muscle weakness
weight gain and easy bruising
cortisol
excessive hairg growth
androen excess
sweating and temulous nesss
excess catecholamines
diarrhea nd flushing
carcinomid syndrome
K levels in pt w/ DKA
normal to increased d/t shift of K OUT of cells
but total K deficit (decreased intracellular level)
*must replace K in these pts
canagliflozin
dapagliflozin
SGLT2 inhibiotrs
block reabsorption of glucose in PCT
SGLT2 inhibitors
what should be monitored before and afer starting thearpy w/ SGLT2 inhibitors
serum creatinine
becomes apparent when serum Ca are less than 7
neuromuscular hyperexcitablity
common cause of hypocalcemia
primary hypoparathyroidism d/t loss of parathyroid tissue during thyroidectomy
drugs assocaited w/ medication induced body fat redistribution syndrome
HIV-1 proteases
glucocorticoids
tamoxifen
raloxifene
SERMS
used for tx of osteoporosis and breast cancer
Tamoxifen–> increases estrogen in bone and uterus but decreases estrogen in breast
ER antagonist associated w/ increased risk of endometrial cancer and thromboembolic disease
Tamoxifen
agonizes uterus
insulin mediated glucose uptake
skeletal muscle
adipocytes w/ glut 4
best option for post meal hyperglycemia
lispro
aspart
glulisine
best basal long acting insulins
glargine and detemir (once a day)
best tx for gestational diabetes in pts whom diet and light exercise wono’t conrol BS levels
insulin
anorexia related amenorhea
begins in hypothalamus NOT pit or ovaries
loss of pulsatile secretion of GnRH from hypo
LH stimulates these cells to produce androgens
theca interna
where are androgens converted to estradiol
FSH stimulation converts androgens to estradiol in Granulosa cells
how does chronic kidney disease lead to low vitamin D
conversion of 25 OH to 1,25 OH is impaired
first hydroxylation step cholecalciferol to 25 hydrocholecalciferol occurs hwere?
liver
mononucleur parenchymal infiltrate w/ well developed germ centers
hasimotos
branching papillary structures w/ concentric calcifications (psammoma bodies)
papillary thyroid cacncer
mixed cellular infiltrate w/ MNGC
de quervians thyroiditis
extensive fibrosis of thyroid gland
riedels
infiltrative dermopathy and exopthalmos
caused by AR against thyrotropin receptor that leads to accumulation of glycosaminoglycans in affected tissues
Grave disease