Respiratory 24

Question 1

What are the two forms that O2 is carried in?

Answer 1

1. Dissolved in plasma (2%)

2. Combined with hemoglobin (98%)

Question 2

What is Hemoglobin characterized by?

Answer 2

Four amino acid subunits. Two alpha chains and two beta chains. And four heme groups

Question 3

What does each Heme group have?

Answer 3

A Porphyrin ring structure that contains an iron atom in the ferrous form to which O2 binds

Question 4

How many oxygen can each hemoglobin molecule bind to?

Answer 4

Up to 4 O2 molecules

Question 5

What does the Oxygen Dissociation curve depict?

Answer 5

The interaction between hemoglobin and the arterial partial pressure of oxygen

Question 6

What is the difference in hemoglobin saturation when blood leaves the pulmonary capillaries and when it leaves peripheral tissues?

Answer 6

After leaving pulmonary capillaries saturation is 100% and after leaving peripheral tissues saturation is 75%

Question 7

What is O2 Capacity?

Answer 7

The max amount of O2 that can be combined with Hb

Question 8

What is the O2 capacity dependant on?

Answer 8

How much hemoglobin is present in the blood

Question 9

What is Hb Saturation?

Answer 9

The percentage of the available Hb binding sites that have O2 attatched

Question 10

What is the most important factor that influences hemoglobin saturation?

Answer 10

Arterial PO2. But PH, PCO2 and temperature also influence Hb saturation