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Physl Part 2 > GI 13a > Flashcards

GI 13a Flashcards

1
Q

What are the four components of gastric secretions?

A
  • Mucus
  • HCl
  • Enzymes
  • Hormones
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2
Q

What does the Mucus gastric secretion do?

A

Lubricates and protects stomach lining

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3
Q

What does the HCl stomach secretion do?

A
  • Solubilizes some food
  • Kills ingested microbes
  • Cleaves pepsinogen
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4
Q

What does the pepsinogen stomach secretion do?

A

Gets converted to Pepsin and cleaves proteins

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5
Q

Where do the hormones secreted by the stomach go?

A

Into the blood stream

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6
Q

What cleaves Pepsinogen?

A

HCl

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7
Q

What cells produce mucus in the stomach?

A

Surface mucous cells

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8
Q

Which cells in the stomach secrete HCl?

A

Parietal cells

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9
Q

What do ECL cells in the stomach secrete?

A

Histamines

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10
Q

What do chief cells in the stomach secrete?

A

Pepsinogen

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11
Q

What is HCl production mediated by?

A

Cephalic and Gastric Phase responses

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12
Q

What stimulates HCl production?

A

Gastrin, Histamine and ACh

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13
Q

What is HCl production inhibited by?

A

Somatostatin

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14
Q

How do the regulators of HCl production work?

A

They will either stimulate or inhibit the docking of a hydrogen potassium ATPase pump to the cell wall increasing or decreasing proton pumps activity

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15
Q

What are G-cells?

A

Enteroendocrine cells on the gastric epithelium

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16
Q

What stimulates G cells to secrete gastin?

A

Protein rich meals and amino acids

17
Q

What does Gastrin released by G cells do?

A

Go into the circulation and influence ECL cells to increase histamine production and parietal cells to increase HCl

18
Q

What does increased histamine release by ECL do?

A

Signals the parietals cells to increase acid production

19
Q

What are the two main components of pancreatic secretions?

A
  • Bicarbonate

* Enzymes

20
Q

What is the function of the bicarbonate released by the pancreas?

A

To neutralize chyme

21
Q

What are the exocrine cells of the pancreas?

A

Acinar cells

22
Q

What are Acinar cells responsible for?

A

Production of pancreatic enzymes

23
Q

What are duct cells in the pancreas responsible for?

A

Bicarbonate secretion

24
Q

What does the pancreatic duct merge with?

A

The common bile duct

25
Q

What does the Sphincter of Oddi control?

A

The release of bile and pancreatic juice into the SI

26
Q

What increases secretin production from the SI?

A

High acidity

27
Q

What does SEcretin do?

A

Causes the pancreas to increase bicarbonate secretion

28
Q

What causes increased CKK secretion?

A

High protein meals

29
Q

How does increased CCK affect the pancreas?

A

It causes the pancreas to produce more enzymes

Physl Part 2 (96 decks)

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