GI 22 Flashcards
1
Q
What prevents the stomach from digesting itself?
A
- Alkaline bicarbonate mucus
- Tight junctions
- High turnover of cells
2
Q
What can breakdown of the gastric epithelium cause?
A
The formation of ulcers
3
Q
Which bacteria causes stomach ulcers?
A
Helicobacter Pylori
4
Q
What are the ways stomach ulcers can be diagnosed?
A
- Medical history & physical exam
- Laboratory test for H. Pylori infection
- Endoscopy
- Barium meal x-ray
5
Q
What is the treatment for ulcers?
A
- Antibiotics
- Antacid
- Inhibition of stomach acid
6
Q
What are the two ways stomach acid can be inhibited?
A
- Histamine blockers - Block specific histamine receptors found on parietal cells
- Proton pump inhibitors - Direct inhibit proton potassium ATPase on the membrane of parietal cells that secrete protons into the stomach
