Respiratory 15 Flashcards
What is Lung Compliance determined by?
- Elastic components of lungs and airway tissue
* Surface tension at the air water interface within the alveoli
Where are elastin and collagen located in the lungs?
Between the different alveoli around blood vessels and bronchi
What can the elastin and collagen in the lungs influence?
How stiff the lung is
What are the characteristics of elastin?
- Weak spring
- Low tensile strength
- Extensible
What are the characteristics of collagen?
- Strong twine
- High tensile strength
- Inextensible
Which properties does collagen give more of?
Stiffness
Increasing what elastic component of the lung gives fibrosis?
Collagen
What is floppy lungs the result of?
Elastin destruction and alveolar wall destruction
What happens with changes in transpulmonary pressure and volume in floppy lungs?
For little changes in Ptp there are large changes in lung volume
What are the Alveoli like in people with emphysema?
In people with emphysema there are large alveolar spaces and reduced area for gas exchange
What causes the floppy lung in emphysema?
The elastin being eliminated
Which elastic molecule is Pulmonary Fibrosis caused by?
Collagen deposition
How is Transpulmonary pressure affected by Pulmonary fibrosis?
Higher transpulmonary pressures are necessary to generate changes in lung volume