Endocrinology 6 Flashcards
What are the three places that Growth Hormone affects Metabolism?
- Fats
- Carbohydrates
- Proteins
How does Growth Hormone affect fats?
It increases lipolysis and usage free fatty acids for energy
How does Growth Hormone affect carbohydrates?
It decreases glucose uptake into cells causing hyperglycemia
How does Growth Hormone affect proteins?
It increases amino acid uptake into cells and increases protein synthesis and cell size
What are the three groups that cause Growth Hormone Secretion?
- Hormones
- Metabolic control
- Other
What is the Hormonal control of Growth Hormone (increased secretion)?
- GHRH
* Ghrelin
What is the Hormonal control of Growth Hormone (decreased secretion)?
- Somatostatin
- Growth Hormone
- IGF
What metabolic control of growth hormone increases secretion?
Hypoglycemia and increased amino acids
What metabolic control of growth hormone decreases secretion?
Hyperglycemia and increased fatty acids
What are other controls of Growth Hormone Secretion that increase secretion?
Deep sleep and stress (exercise)
What are other controls of Growth Hormone Secretion that decrease secretion?
Ageing
What can too much growth hormone cause?
- Gigantism
* Acromegaly
What can too little growth hormone cause?
- Dwarfism
* Metabolic effects
What is the difference between Gigantism and Acromegaly?
Gigantism occurs in children and Acromegaly occurs in adults
What is Gigantism?
Increased linear growth
