Final Exam - Parkinson's & Alzheimer's TT Flashcards

1
Q

Treatment of Parkinson’s

A

1) Drugs that are synthesized to dopamine
2) Promote the release of existing stores of dopamine
3) Directly stimulate dopamine receptors
4) Inhibit the degradation of dopamine in the terminal neuron
5) Anticholinergics decrease acetylcholine

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2
Q

Drugs That Are Synthesized to Dopamine Examples

A
  • levodopa/carbidopa
  • levodopa/benserazide
  • levodopa/carbidopa/entacapone
  • entacapone
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3
Q

Brand:

  • Sinemet
  • Sinemet CR
A

Generic: levodopa/carbidopa

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4
Q

Brand: Prolopa

A

Generic: levodopa/benserazide

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5
Q

Brand: Stalevo

A

Generic: levadopa/carbidopa/entacapone

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6
Q

Brand: Comtan

A

Generic: entacapone

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7
Q

Drugs That Promote Release of Existing Stores of Dopamine Examples

A

-amantadine

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8
Q

Brand:

  • amantadine
  • Symmetrel
A

Generic: amantadine

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9
Q

Drugs That Stimulate Dopamine Receptors Examples

A
  • bromocriptine
  • pramipexole
  • ropinirole
  • rotigotine
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10
Q

Brand:

  • bromocriptine
  • Parlodel
A

Generic: bromocriptine

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11
Q

Brand: Mirapex

A

Generic: pramipexole

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12
Q

Brand: Requip

A

Generic: ropinerole

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13
Q

Brand: Neupro Patch

A

Generic: rotigotine

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14
Q

Drugs That Inhibit The Degradation of Dopamine Examples

A
  • selegeline

- rasagiline

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15
Q

Brand:

  • selegeline
  • Eldepryl
A

GEneric: selegiline

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16
Q

Brand: Azilect

A

Generic: rasagiline

17
Q

Anticholinergic Drugs Examples

A
  • benztropine

- trihexyphenidyl

18
Q

Brand:

  • benztropine
  • Cogentin
A

Generic: benztropine

19
Q

Brand:

  • trihexyphenidyl
  • Artane
A

Generic: trihexyphenidyl

20
Q

Other Drugs Used For Parkinson’s

A
  • ethopropazine

- procyclidine

21
Q

Brand: Parsitan

A

Generic: ethopropazine

22
Q

Brand:

  • procyclidine
  • Procyclid
A

Generic: procyclidine

23
Q

Anti-Parkinson Drugs Warning Labels

A
  • MAY CAUSE DIZZINESS
  • LIMIT ALCOHOL
  • DO NOT D/C WITHOUT MEDICAL SUPERVISION
  • AVOID VITAMINS AND IRON SUPPLEMENTS WITHIN 2 HOURS (levodopa/carbidopa)
  • SWALLOW WHOLE; DONT CRUSH OR CHEW
  • TAKE WITH FOOD (bromocriptine)
  • MAY DISCOLOR URINE (Stalevo)
24
Q

Treatment of Alzheimer’s

A
  • AChE Inhibitors

- NMDA Receptor Inhibitors

25
Q

AChE Inhibitors Examples

A
  • donepezil
  • galantamine
  • rivastigmine
26
Q

Brand:

  • Aricept
  • Aricept RDT
A

Generic: donepezil

27
Q

Brand: Reminyl ER

A

Generic: galantamine

28
Q

Brand:

  • Exelon
  • Exelon Patch
A

Generic: rivastigmine

29
Q

NMDA Receptor Inhibitor Example

A

-memantine

30
Q

Brand: Ebixa

A

Generic: memantine

31
Q

AChE Inhibitors Warning Labels

A
  • MAY CAUSE DIZZINESS
  • TAKE WITH FOOD
  • DONT D/C WITHOUT MEDICAL SUPERVISION
  • MAINTAIN ADEQUATE HYDRATION (galantamine)
  • SWALLOW WHOLE; DONT CRUSH OR CHEW (rivastigmine)
32
Q

Memantine Warning Labels

A
  • MAY CAUSE DIZZINESS

- DONT D/C WITHOUT MEDICAL SUPERVISION