Final Exam - Parkinson's & Alzheimer's TT Flashcards
Treatment of Parkinson’s
1) Drugs that are synthesized to dopamine
2) Promote the release of existing stores of dopamine
3) Directly stimulate dopamine receptors
4) Inhibit the degradation of dopamine in the terminal neuron
5) Anticholinergics decrease acetylcholine
Drugs That Are Synthesized to Dopamine Examples
- levodopa/carbidopa
- levodopa/benserazide
- levodopa/carbidopa/entacapone
- entacapone
Brand:
- Sinemet
- Sinemet CR
Generic: levodopa/carbidopa
Brand: Prolopa
Generic: levodopa/benserazide
Brand: Stalevo
Generic: levadopa/carbidopa/entacapone
Brand: Comtan
Generic: entacapone
Drugs That Promote Release of Existing Stores of Dopamine Examples
-amantadine
Brand:
- amantadine
- Symmetrel
Generic: amantadine
Drugs That Stimulate Dopamine Receptors Examples
- bromocriptine
- pramipexole
- ropinirole
- rotigotine
Brand:
- bromocriptine
- Parlodel
Generic: bromocriptine
Brand: Mirapex
Generic: pramipexole
Brand: Requip
Generic: ropinerole
Brand: Neupro Patch
Generic: rotigotine
Drugs That Inhibit The Degradation of Dopamine Examples
- selegeline
- rasagiline
Brand:
- selegeline
- Eldepryl
GEneric: selegiline
Brand: Azilect
Generic: rasagiline
Anticholinergic Drugs Examples
- benztropine
- trihexyphenidyl
Brand:
- benztropine
- Cogentin
Generic: benztropine
Brand:
- trihexyphenidyl
- Artane
Generic: trihexyphenidyl
Other Drugs Used For Parkinson’s
- ethopropazine
- procyclidine
Brand: Parsitan
Generic: ethopropazine
Brand:
- procyclidine
- Procyclid
Generic: procyclidine
Anti-Parkinson Drugs Warning Labels
- MAY CAUSE DIZZINESS
- LIMIT ALCOHOL
- DO NOT D/C WITHOUT MEDICAL SUPERVISION
- AVOID VITAMINS AND IRON SUPPLEMENTS WITHIN 2 HOURS (levodopa/carbidopa)
- SWALLOW WHOLE; DONT CRUSH OR CHEW
- TAKE WITH FOOD (bromocriptine)
- MAY DISCOLOR URINE (Stalevo)
Treatment of Alzheimer’s
- AChE Inhibitors
- NMDA Receptor Inhibitors
AChE Inhibitors Examples
- donepezil
- galantamine
- rivastigmine
Brand:
- Aricept
- Aricept RDT
Generic: donepezil
Brand: Reminyl ER
Generic: galantamine
Brand:
- Exelon
- Exelon Patch
Generic: rivastigmine
NMDA Receptor Inhibitor Example
-memantine
Brand: Ebixa
Generic: memantine
AChE Inhibitors Warning Labels
- MAY CAUSE DIZZINESS
- TAKE WITH FOOD
- DONT D/C WITHOUT MEDICAL SUPERVISION
- MAINTAIN ADEQUATE HYDRATION (galantamine)
- SWALLOW WHOLE; DONT CRUSH OR CHEW (rivastigmine)
Memantine Warning Labels
- MAY CAUSE DIZZINESS
- DONT D/C WITHOUT MEDICAL SUPERVISION
