Final Exam Flashcards - Viral Infection

Question 1

Examples of viral Infections

Answer 1

• Common cold
• Warts
• HIV
• Smallpox, measles, etc
• Hepatitis A, B, C
• HPV
• Rotavirus

Question 2

Antivirals MOA

Answer 2

• Inhibit viral replication
• Virostatic; Do not destroy viruses
• Slow the virus down so the immune system can fight it

Question 3

Treatment and Prevention of Influenza

Answer 3

• amantadine; for influenza A only

- oseltamavir and zanamivir; treat influenza A and B (must be started within 48 hours of symptom onset)

Question 4

Amantadine ADR’s

Answer 4

• Anxiety
• Drowsiness or insomnia
• Confusion
• Headache
• Diarrhea or constipation
• N/V

Question 5

Oseltamivir and Zanamivir ADR’s

Answer 5

-Coughing
-Dizziness
-Neural complications
-Headache
-Psychosis
Zanamivir specific:
-Bronchospasm in people with asthma
-Contraindicated in pregnancy

Question 6

Treatment of Hepatitis B and C Viruses

Answer 6

• Interferons
• Nucleoside analogs
• Nucleotide analogs
• Protease inhibitors

Question 7

Interferons

Answer 7

• Inhibitors of transcription

- For both hepatitis B and C

Question 8

Interferons ADR’s

Answer 8

-Serious drop in platelets and WBCs
-Depression
-Fever
-Chills
N/V
-Dizziness
-Headache
-Diarrhea

Question 9

Inhibition of DNA and RNA Replication

Answer 9

• Common Ending for Antivirals used for herpes is: “cyclovir” or “ciclovir”
• Antivirals that inhibit DNA and RNA replication are used for the treatment of herpes simplex type 1 and type 2, herpes zoster, varicella zoster, etc.

Question 10

Antivirals For Herpes ADR’s

Answer 10

• Diarrhea
• N/V
• Headache
• Fatigue
• Dizziness
• Confusion

Question 11

HIV

Answer 11

• Virus that attacks the immune system, resulting in a chronic and progressive disease that leaves people vulnerable to infections
• Once the body can no longer fight the infection, it has become AIDS