Final Exam Flashcards - Glaucoma
1
Q
Glaucoma
A
-Ciliary body continually produces aqueous humor which can put pressure on the optic nerve and cause vision loss
2
Q
Open Angle vs. Angle Closure Glaucoma
A
- Open Angle: Abnormal accumulation of aqueous humor
- Angle closure: Aqueous humor drainage is impaired
3
Q
Pharmacological Treatment of Glaucome
A
- Decrease formation of aqueous humor
- Increase drainage of aqueous humor
4
Q
Drugs That Decrease Aqueous Humor Formation
A
- B-blockers
- A-Adrenergic agonists
- Carbonic anhydrase inhibitors
5
Q
B-Blockers
A
- Common ending: “olol”
- Decrease Aqueous humor by inhibiting the action of epinephrine and norepinephrine of blood vessels in ciliary body of the eye
6
Q
A-Adrenergic Antagonists
A
- Reduce blood flow in ciliary body
- Reduce formation of aqueous humor
- also increase aqueous humor outflow
7
Q
Carbonic Anhydrase Inhibitors
A
- common ending: “zolamide”
- Decrease pressure by decreasing the rate of production of aqueous humor
8
Q
Drugs That Promote Drainage of Aqueous Humor
A
- A-adrenergic agonists
- Cholinergic agonists
- Prostaglandin analogs
9
Q
Cholinergic Agonists
A
- Bind to receptors and mimic acetylcholine
- Binding contracts ciliary muscles and pupil
10
Q
Prostaglandin Analogs
A
- Common ending: “prost”
- Relax ciliary muscles to permit drainage of aqueous humor
11
Q
Prostaglandin Analogs ADR’s
A
-Permanent changes in eye color and may thicken eyelashes
