Final Exam Flashcards - Fungal Infections

Question 1

Athlete’s Foot

Answer 1

• Tinea pedis

- Flaking, itching, burning, peeling of skin especially between toes

Question 2

Onychomycosis

Answer 2

-Fungal infections of the nails

Question 3

Vulvovaginal Candidiasis

Answer 3

-Yeast infections

Question 4

Oral Candidiasis (Thrush)

Answer 4

• Candida infection of the oral cavity

- Can be caused by inhaled corticosteroids

Question 5

Antifungal Classifications

Answer 5

• Imidazoles and triazoles
• Allylamines
• Polyenes
• Thiocarbamates
• Echinocandins
• Misc.

Question 6

Imidazoles And Triazoles

Answer 6

• Common ending: “azoles”

- Can be OTC or Rx

Question 7

Topical “azoles” ADR’s

Answer 7

• Burning
• Irritation
• Stinging

Question 8

Fluconazole ADR’s

Answer 8

• Headache
• Nausea
• Stomach pain
• CONTRAINDICATED IN PREGNANCY
• NO GRAPEFRUIT
• MANY DRUG INTERACTIONS

Question 9

Allylamine Antifungals

Answer 9

-Stunt the growth of fungi by blocking an enzyme needed for the synthesis of ergosterol

Question 10

Allylamine Antifungals (terbinafine) ADR’s

Answer 10

• Liver toxicity
• Headache
• Taste and smell disturbances

Question 11

Polyene Antifungals

Answer 11

-Inhibit synthesis of the fungal cell membrane

Question 12

Thiocarbamates

Answer 12

• Tolnaftate

- Stunts growth of dermatophytes

Question 13

Echinocandin Antifungals

Answer 13

• anidulafungin, caspofungin, micafungin
• Formulated for parenteral use
• all require refrigeration