Final Exam Flashcards - Cancer
1
Q
Cancer
A
- A disease that occurs when the normal cell renewal process fails
- Tumors may be benign or malignant
2
Q
Treatment of Cancers
A
- Chemotherapy
- Biological therapy
- Radiation therapy
- Surgery
3
Q
Chemotherapy
A
-Use of drugs to kill or slow the growth of cancerous cells
4
Q
Biological Therapy
A
-Administration of immunomodulators to boost the body’s natural defense
5
Q
Chemotherapeutic Agents/Antineoplastic Agents MOA
A
-Work by various mechanisms to interrupt the cell replication cycle
6
Q
Types of Breast Cancer
A
- Hormone Receptor-Positive
- HER2-Positive
- Triple Negative
7
Q
Breast Cancer Treatment
A
-Hormone therapy is the treatment of choice for breast cancer
8
Q
Classification of Hormone Therapy
A
- SERMs
- Estrogen receptor down-regulators
- Aromatase inhibitors
- GnRH
- Progestins
9
Q
SERMs
A
-tamoxifen
10
Q
SERMs ADRs
A
- Lowered platelet and WBC count
- Hair loss
- Menstrual changes
- Pulmonary embolism
- Deep vein thrombosis
- N/V
- Hot flashes
- Vaginal itchiness
- Endometrial cancer
11
Q
ER Down-Regulators
A
-fulvestrant
12
Q
Fulvestrant ADR’s
A
- Bone and back pain
- hot flashes
- N/V
- Diarrhea
13
Q
Aromatase Inhibitors
A
-Block the conversion of androgens to estrone and estradiol
14
Q
Aromatase Inhibitors ADR’s
A
- Menopause like symptoms
- N/V
- Dizziness
- Cough
- Headache
- Hair loss
- Bone pain
15
Q
LNRH and GnRH Agonists
A
-goserelin
