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Pharmacology and Therapeutic Terminology > Acne - Chapter 41 > Flashcards

Acne - Chapter 41 Flashcards

1
Q

Acne Vulgaris

A

-A disorder resulting from action of hormones and other substances on the skins sebaceous glands and hair follicles that leads to clogged pores and breakouts

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2
Q

Comedones

A

-Enlarged, plugged hair follicles

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3
Q

Treatment Goals For Acne

A
  • Heal existing lesions
  • Stop new lesions from forming
  • Prevent scarring
  • Minimize psychological stress and embarrassment
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4
Q

Treatment of Mild Acne

A
  • Mild soap and water with gentle cleansing

- Topical OTC medicines containing keratolytics (salycilic acid, benzoyl peroxide)

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5
Q

Salicylic Acid

A
  • Helps break down blackheads and whiteheads

- helps cut down the shedding of cells lining the hair follicles

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6
Q

Brand: Various OTC products including Clearasil

A

Generic: salicylic acid

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7
Q

Benzoyl Peroxide

A
  • Most widely used OTC medication
  • Prevents closure of the pilosebacious duct
  • promotes increased sloughing and resolution of comedones
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8
Q

Brand: Benzac AC, Benzac W, Benzagel, Clearasil, Clean and Clear, Panoxyl, Proactiv

A

Generic: benzoyl peroxide

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9
Q

Treatment of

Moderate Acne

A
  • Oral and/or topical antibiotics
  • prescription strength topical keratolytics
  • Vitamin A derivatives
  • Oral contraceptives
  • Physical methods
  • UV light therapy
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10
Q

Oral Antiinfectives for Moderate Acne (Systemic)

A
  • tetracycline
  • doxycycline
  • minocycline
  • clindamycin
  • sulfonamides
  • erythromycin
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11
Q

Brand: Apprilon, Doxycin, Vibra-Tabs, Vibramycin

A

Generic: doxycycline

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12
Q

Brand: erythromycin

A

Generic: erythromycin

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13
Q

Brand: minocin

A

Generic: Minocycline

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14
Q

Brand: tetracycline

A

Generic: tetracycline

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15
Q

Topical Antiinfectives for Moderate Acne Examples

A
  • sulfacetamide/sulfur
  • clindamycin
  • benzoyl peroxide/clindamycin
  • benzoyl peroxide/erythromycin
  • azelaic acid
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16
Q

Brand: Sulfacet-R

A

Generic: sulfacetamide/sulfur

17
Q

Brand: Clindets, Dalacin T

A

Generic: clindamycin

18
Q

Brand: Benzaclin, Clindoxyl, Clindoxyl ADV

A

Generic: benzoyl peroxide/clindamycin

19
Q

Brand: Benzamycin

A

Generic: benzoyl peroxide/erythromycin

20
Q

Brand: Finacea

A

Generic: azelaic acid

-Keratolytic

21
Q

Acne Rosacea

A
  • Blood vessels of the face become swollen after repeated exposure to certain triggers
  • Starts as simple blushing, but advances into bumps on the face that look like acne
22
Q

Topical Retinoids for Moderate Acne

A

-Retinoids are vitamin A derivatives

23
Q

Topical Retinoids Examples

A
  • tretinoin
  • tretinoin/erythromycin
  • tretinoin/clindamycin
  • adapalene
  • adapalene/benzoyl peroxide
  • tazarotene
24
Q

Brand: Retin-A, Retin-A Micro,Stieva-A, Vitamin-A Acid

A

Generic: tretinoin

25
Q

Brand: Stievamycin

A

Generic: tretinoin/erythromycin

26
Q

Brand: Biacna

A

Generic: tretinoin/clindamycin

27
Q

Brand: Differin, Differin XP

A

Generic: adapalene

28
Q

Brand: TactuPump, TactuPump Plus

A

Generic: adapaline/benxoyl peroxide

29
Q

Brand: Tazorac

A

Generic: tazarotene

-Retinoid prodrug

30
Q

Treatment of Severe Acne

A
  • Drainage and surgical excision
  • Interlesional corticosteroid injection
  • Oral Retinoid
  • Oral antibiotics
  • Oral contraceptives
31
Q

Isotretinoin

A
  • Reduces production of sebum and shrinks sebaceous glands
  • Stabilizes and prevents comodones
  • Alters DNA transcription
32
Q

Brand: Accutane, Epuris

A

Generic: isotretinoin

33
Q

Isotretinoin Restricitons

A
  • NO PREGNANCY
  • Category X
  • Strongly encouraged to dispense 1 month supply only
  • Must have monthly liver function tests
34
Q

Isotretinoin ADR’s

A
  • Extreme dryness of eyes, mouth, nose, lips, and skin
  • Changes in mood and depression
  • Poor night vision
  • Impaired liver function
  • Hyperglycemia
  • Photosensitivity
  • Fetal deformities
35
Q

Isotretinoin Warning Labels

A
  • TAKE WITH FOOD
  • AVOID PROLONGUES EXPOSURE TO SUNLIGHT
  • AVOID PREGNANCY
36
Q

Treatments for Hormonally Influenced Acne in Women

A

-In some women acne is caused by an excess of androgen hormones

37
Q

Hormonally Influenced Acne Drugs Examples

A
  • oral contraceptives
  • spironolactone
  • ethinyl estradiol/cyproterone
38
Q

Brand: Aldactone

A

Generic: spironolactone

39
Q

Brand: Diane

A

Generic: ethinyl estradiol/cyproterone

Pharmacology and Therapeutic Terminology (97 decks)

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