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Pharmacology and Therapeutic Terminology > Final Exam Flashcards - Reproductive > Flashcards

Final Exam Flashcards - Reproductive

1
Q

Intrauterine Device (IUD)

A
  • > 99% effective
  • 2 categories: copper based, hormone based
  • DO NOT PROTECT AGAINS STI’s
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2
Q

IUD MOA

A
  • Prevents fertilization
  • Copper IUD stops sperm from making their way through the uterus into the fallopian tubes
  • Progestin releasing IUD thickens cervical mucus and thins endometrial lining
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3
Q

Hormonal IUD’s

A
  • Release levonorgestrel

- Decrease menstrual flow and cramping

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4
Q

Hormonal IUD’s ADR’s

A
  • Acne
  • Weight gain
  • Headache
  • Spotting for first 3 months
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5
Q

Oral Contraceptives

A
  • contain a combination of an estrogen + a progestin OR a progestin only
  • “mini-pill” contains only progestin
  • Should be taken at the same time each day
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6
Q

OCP MOA

A
  • FSH and LH secretion is inhibited through negative feedback
  • Mature follicles do not develop and ovulation is prevented
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7
Q

Oral contraceptives ADR’s

A
  • DVT
  • thromboembolism
  • MI/Stroke
  • Appetite loss
  • N/V
  • Spotting
  • Breast tenderness
  • Signs of vaginal infection
  • Blurred vision
  • Weight gain
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8
Q

OCP Contraindications-

A
  • Pregnancy
  • Breastfeeding
  • Smokers >35 yr
  • <6 weeks post-partum
  • Hypertension
  • Focal migraine
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9
Q

Progestin Only OCP

A
  • Known as minipill
  • Used if there is intolerance to estrogen
  • **Critical to take on time
  • norethindrone
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10
Q

Non-Oral Hormonal Contraceptives

A
  • Depo-Provera is a progestin only hormone injection given by a health care professional every 12 weeks
  • Evra Patch: applied each week for 3 weeks then 1 week patch free
  • NuvaRing: insert 1 ring for 3 weeks, then remove for 1 week
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11
Q

Emergency Contraception

A
  • Safe and effective way to prevent pregnancy after unprotected intercourse
  • High dose of levonorgestrel
  • Must be taken within 72 hours
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12
Q

Emergency Contraception MOA

A
  • Delays or prevents ovaries from releasing an egg
  • alters cervical mucus
  • Changes uterine lining
  • slows movement of sperm and egg through fallopian tube
  • Will NOT terminate pregnancy
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13
Q

Menopause

A

-Termination of the menstrual cycle

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14
Q

Hormone Replacement Therapy

A

-Typically involves administration of oral or vaginal estrogens to minimize symptoms of menopause

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15
Q

HRT ADR’s

A
  • Increased risk of breast cancer, coronary artery disease, blood clots, stroke
  • N/V
  • Cramping
  • Breast tenderness
  • Migraine headaches
  • Return of menstruation or spotting
  • Weight gain
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16
Q

PMDD

A
  • Severe form of PMS

- Treated with antidepressants

17
Q

Dysmenorrhea

A

-Painful menstruation

18
Q

Amenorrhea

A
  • Absence of normal menstruation
  • Primary: failure of menstruation cycles to begin
  • Secondary: slows to 3-4 cycles per year
19
Q

Infertility

A

-Failure to conceive after 1 year of regular unprotected intercourse

20
Q

Treatment of Infertility

A
  • Antiestrogens
  • Gonadotropins
  • GnRH antagonists
  • GnRH agonists
  • Progesterone
21
Q

Gonadotropins ADR’s

A
  • Headache
  • Lightheadedness
  • Nausea
  • Flushing
  • Local inflammation at injection site
22
Q

Clomiphene ADR’s

A
  • Visual disturbances
  • Dizziness
  • Multiple births
23
Q

Treatment of Androgen Deficiency in Males

A
  • Testosterone and its derivatives

- Anabolic-androgenic steroids

24
Q

Androgenic-Anabolic Steroid ADR’s

A
  • Gynecomastia
  • Testicular atrophy
  • Impotence
  • Nausea
  • Depression
  • Acne
  • Anxiety
25
Q

Endometriosis

A

-Benign but very painful condition characterized by functioning endometrial tissue outside of the uterus

26
Q

Treatment of Endometriosis

A
  • Combined OCP’s
  • Progestins
  • Danazol
  • GnRH agonists
27
Q

Endometriosis Treatment ADR’s

A
  • Headache
  • Tumor flare
  • Gynecomastia
  • Postmenopausal symptoms
  • Vaginal spotting
  • GI distress
  • Menstrual irregularities

Pharmacology and Therapeutic Terminology (97 decks)

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