Final Exam Flashcards - Allergies

1
Q

Allergy

A
  • A hypersensitivity reaction by the immune system upon exposure to an allergen
  • Allergic reaction can occur anywhere: upper or lower respiratory tract, eyes, skin, digestive tract, etc.
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2
Q

Anaphylaxis

A

-A life threatening allergic reaction

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3
Q

Treatment of Anaphylaxis

A

-epinephrine

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4
Q

Drug Treatment of Allergies

A
  • Antihistamines
  • Intranasal corticosteroids
  • Oral or IV corticosteroids
  • Mast cell stabilizers
  • Leukotriene receptor antagonists
  • Immunotherapy
  • Vasoconstrictors
  • Topical corticosteroids
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5
Q

Antihistamines

A
  • Prevent binding at H1 receptor sites

- First or second generation

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6
Q

First Generation Antihistamines

A
  • Non-selective/Classical

- OTC or Rx

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7
Q

First Generation Antihistamines ADR’s

A
  • Sedating
  • Possible thickening of mucus
  • Anticholinergic effects of dry mouth, pupil dilation, urinary retention, increased ocular pressure
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8
Q

First Generation Antihistamines Tech Note!

A

-Should be used cautiously in men with prostate disease, people with glaucoma, people with asthma, and women who are breast feeding

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9
Q

Second Generation Antihistamines

A
  • Selective

- OTC and Rx

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10
Q

Second Generation Antihistamines ADR’s

A

-10% experience sedation with cetirizine

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11
Q

Intranasal Corticosteroids

A
  • Inhibit onset of inflammatory response
  • Reduce the number of inflammatory cells
  • All are Rx except triamcinolone
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12
Q

Intranasal Corticosteroids ADR’s

A
  • Nasal burning or throat stinging
  • Throat irritation
  • Nose bleed
  • Nasal candida infection
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13
Q

Mast Cell Stabilizers

A
  • Cromolyn sodium is the only mast cell stabilizer available for intranasal use
  • Administered to reduce nasal reactivity to allergens
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14
Q

Leukotriene Receptor Antagonists

A
  • montelukast

- zafirlukast

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15
Q

Immunotherapy

A

-Allergy shots

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16
Q

Vasoconstrictors (for nasal allergy congestion)

A

-Alleviate nasal congestion caused by allergic rhinitis by constricting blood vessels in the nose which results in decreased inflammation and decreased fluid