Final Exam Flashcards - Psychology
4 Major Types of Anxiety Disorders
- Generalized anxiety disorder (GAD)
- Panic disorder
- Obsessive Compulsive Disorder (OCD)
- Post Traumatic Stress Disorder (PTSD)
Pharmaceutical Treatment of Anxiety Disorders
Drugs that affect the neurotransmitters:
- Y-aminobutyric acid (GABA)
- Serotonin (5-HT)
- Norepinephrine (NE)
Benzodiazepines
- Enhance binding of GABA
- Have a high degree of lipid solubility
- Common ending: “epam” & “olam”
3 Primary Types of Depression
- Major depression
- Bipolar Disorder
- Dysthymia
Major Depression
- AKA clinical depression
- Persistent feelings of sadness, emptiness, or hopelessness usually accompanied by fatigue, lack of interest, irritability, insomnia or hypersomnia, etc.
Bipolar Disorder
- AKA manic depressive disorder
- Associated with mood swings between depression and periods of mania
Dysthymia
-Produces symptoms that are similar to major depression; however, they are less severe
Biogenic Amine Theory
- Clinical depression results from a decrease in monoamine neurotransmitters in the brain, especially NE, Dopamine, and serotonin.
- In bipolar disorder, the manic phase is believed to be associated with increased levels of monoamine neurotransmitters
Tricyclic Antidepressants
-Block the reuptake of NE and 5-HT
ADR’s: Photosensitivity and cardiotoxicity
ADR’s Related to Blockade of Histaminic Receptors
- Sedation
- Weight gain
- Hypotension
ADR’s Related to Blockade of Muscarinic Receptors
- Dry mouth
- Blurred vision
- Constipation
- Urinary retention
- Confusion
Selective Serotonin Reuptake Inhibitors (SSRI’s)
- Selectively inhibit the reuptake of serotonin at the synaptic cleft
- Most widely prescribed antidepressants
- Equally effective as TCA’s, yet lack cardiotoxic effects
SSRI’s ADR’s
- Decreased appetite
- Nausea
- Agitation or anxiety
- Diarrhea
- Sexual dysfunction
- Suicide ideation
Serotonin-Norepinephrine Reuptake inhibitors
-Inhibit the reuptake of 5-HT and NE
SNRI ADR’s
- Sedation
- Dizziness
- Nausea
- Insomnia
- Dry mouth
- Increased BP