Final Exam - Cancers TT Flashcards

1
Q

SERM’s Examples

A

-tamoxifen

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2
Q

Brand:

  • Tamofen
  • Nolvadex D
A

Generic: tamoxifen

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3
Q

Estrogen Receptor Down-Regulators Examples

A

-fulvestrant

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4
Q

Brand: Faslodex

A

Generic: fulvestrant

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5
Q

Aromatase Inhibitors Examples

A
  • anastrazole
  • exemestane
  • letrozole
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6
Q

Brand: Arimidex

A

Generic: anastrazole

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7
Q

Brand: Aromasin

A

Generic: exemestane

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8
Q

Brand: Femara

A

Generic: letrozole

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9
Q

GnRH Agonists Examples

A

-goserelin

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10
Q

Brand: Zoladex

A

Generic: goserelin

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11
Q

Progestin Example

A

-megestrol

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12
Q

Brand: Megace

A

Generic: megestrol

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13
Q

Alkylating agents Examples

A
  • cyclophosphamide
  • chlorambucil
  • busulfan
  • ifosfamide
  • melphalan
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14
Q

Brand:

  • Cytoxan
  • Procytox
A

Generic: cyclophosphamide

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15
Q

Brand: Leukeran

A

Generic: chlorambucil

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16
Q

Brand: Myleran

A

Generic: busulfan

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17
Q

Brand: Ifex

A

Generic: ifosfamide

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18
Q

Brand: Alkeran

A

Generic: melphalan

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19
Q

Taxanes Examples

A
  • docetaxel

- paclitaxel

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20
Q

Brand: Taxotere

A

Generic: docetaxel

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21
Q

Brand: Abraxane

A

Generic: paclitaxel

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22
Q

Taxanes Warning Labels

A
  • DO NOT SHAKE (docetaxel)
  • REFRIGERATE; DO NOT FREEZE (docetaxel)
  • MAY STORE AT ROOM TEMP (paclitaxel)
  • DO NOT MIX IN PVC BAGS OR USE PVC SETS
  • EXERCISE PRECAUTIONS FOR HANDLING
  • AVOID ASPIRINS AND NSAIDS
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23
Q

Vinca Alkaloids Examples

A
  • vinblastine
  • vincristine
  • vinorelbine
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24
Q

Brand: Vinblastine Sulfate Injection

A

Generic: vinblastine

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25
Q

Brand: Vincristine Injection

A

Generic: vincristine

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26
Q

Brand: Navelbine

A

Generic: vinorelbine

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27
Q

Vinca Alkaloids Warning Labels

A
  • REFRIGERATE; DO NOT FREEZE (vinorelbine)
  • AVOID ASPIRIN AND NSAIDS
  • EXERCISE PRECAUTIONS FOR HANDLING, PREPARING, AND ADMINISTERING
  • FATAL IF GIVEN INTRATHECALLY. FOR IV USE ONLY.
28
Q

Anthracyclines Examples

A
  • doxorubicin
  • daunorubicin
  • epirubicin
  • idarubicin
  • mitoxantrone
29
Q

Brand:

  • Adriamycin PFS
  • Caelyx
  • Myocet
A

Generic: doxorubicin

30
Q

Brand: Cerubidine

A

Generic: daunorubicin

31
Q

Brand: Pharmorubicin PFS

A

Generic: epirubicin

32
Q

Brand: Idamycin

A

Generic: idarubicin

33
Q

Brand: Mitoxantrone Injection

A

Generic: mitoxantrone

34
Q

Anthracyclines Warning Labels

A
  • AVOID PREGNANCY
  • PROTECT FROM LIGHT
  • MAY CAUSE DISCOLORATION OF URINE
  • EXERCIZE PRECAUTIONS FOR HANDLING
35
Q

Topoisomerase Inhibitors Examples

A
  • etoposide
  • teniposide
  • irinotecan
  • topotecan
36
Q

Brand: Vepesid

A

Generic: etoposide

37
Q

Brand: Camptosar

A

Generic: irinotecan

38
Q

Brand: Vumon

A

Generic: teniposide

39
Q

Brand: Hycamtin

A

Generic: topotecan

40
Q

Topoisomerase Inhibtors Warning Labels

A

-EXERCISE PRECAUTIONS FOR HANDLING, PREPARING AND ADMINISTERING

41
Q

Platinum Compounds Examples

A
  • carboplatin
  • cisplatin
  • oxaliplatin
42
Q

Brand: Paraplatin

A

Generic: carboplatin

43
Q

Brand: Cisplatin

A

Generic: cisplatin

44
Q

Brand: Eloxatin

A

Generic: oxaliplatin

45
Q

Platinum Compounds Warning Labels

A
  • EXERCISE PRECAUTIONS FOR HANDLING

- PROTECT FROM LIGHT (cisplatin)

46
Q

Fluoropyrimidines Examples

A
  • capecitabine
  • cytarabine
  • fludarabine
  • fluorouracil
  • gemcitabine
47
Q

Brand: Xeloda

A

Generic: capecitabine

48
Q

Brand: Cytosar

A

Generic: cytarabine

49
Q

Brand: Fludara

A

Generic: fludarabine

50
Q

Brand:

  • Efudex
  • 5-FU
A

Generic: fluorouracil

51
Q

Brand: Gemzar

A

Generic: gemcitabine

52
Q

Fluoropyrimidines Warning Labels

A
  • EXERCISE PRECAUTIONS (5-FU, cytarabine, fludarabine, gemcitabine)
  • AVOID PREGNANCY (5-FU, capecitabine)
  • AVOID PROLONGUED EXPOSURE TO SUNGLIGHT (5-FU)
  • ROOM TEMP (gemcitabine)
53
Q

Antimetabolites Examples

A
  • methotrexate
  • mercaptopurine
  • thioguanine
54
Q

Brand: Methotrexate

A

Generic: methotrexate

55
Q

Brand: Purinethol

A

Generic: mercaptopurine

56
Q

Brand: Lanvis

A

Generic: thioguanine

57
Q

Antimetabolites Warning Labels

A
  • DO NOT DRINK ALCOHOL
  • AVOID PROLONGUED EXPOSURE TO SUNLIGHT
  • AVOID PREGNANCY
  • EXERCISE PRECAUTIONS FOR HANDLING ETC.
  • AVOID ASPIRINS AND NSAIDS (mercaptopurine)
58
Q

Misc. Cancer Drugs

A
  • bleomycin
  • dactinomycin
  • hydroxyurea
59
Q

Brand: Blenoxane

A

Generic: bleomycin

60
Q

Brand: Cosmegan

A

Generic: dactinomycin

61
Q

Brand: Hydrea

A

Generic: hydroxyurea

62
Q

Monoclonal Antibodies Examples

A
  • bevacizumab

- trastuzumab

63
Q

Brand: Avastin

A

Generic: bevacizumab

64
Q

Brand: Herceptin

A

Generic: trastuzumab

65
Q

Kinase Inhibitor Example

A

-imatinib

66
Q

Brand: Gleevec

A

Generic: imatinib