Final Exam - Cancers TT Flashcards
SERM’s Examples
-tamoxifen
Brand:
- Tamofen
- Nolvadex D
Generic: tamoxifen
Estrogen Receptor Down-Regulators Examples
-fulvestrant
Brand: Faslodex
Generic: fulvestrant
Aromatase Inhibitors Examples
- anastrazole
- exemestane
- letrozole
Brand: Arimidex
Generic: anastrazole
Brand: Aromasin
Generic: exemestane
Brand: Femara
Generic: letrozole
GnRH Agonists Examples
-goserelin
Brand: Zoladex
Generic: goserelin
Progestin Example
-megestrol
Brand: Megace
Generic: megestrol
Alkylating agents Examples
- cyclophosphamide
- chlorambucil
- busulfan
- ifosfamide
- melphalan
Brand:
- Cytoxan
- Procytox
Generic: cyclophosphamide
Brand: Leukeran
Generic: chlorambucil
Brand: Myleran
Generic: busulfan
Brand: Ifex
Generic: ifosfamide
Brand: Alkeran
Generic: melphalan
Taxanes Examples
- docetaxel
- paclitaxel
Brand: Taxotere
Generic: docetaxel
Brand: Abraxane
Generic: paclitaxel
Taxanes Warning Labels
- DO NOT SHAKE (docetaxel)
- REFRIGERATE; DO NOT FREEZE (docetaxel)
- MAY STORE AT ROOM TEMP (paclitaxel)
- DO NOT MIX IN PVC BAGS OR USE PVC SETS
- EXERCISE PRECAUTIONS FOR HANDLING
- AVOID ASPIRINS AND NSAIDS
Vinca Alkaloids Examples
- vinblastine
- vincristine
- vinorelbine
Brand: Vinblastine Sulfate Injection
Generic: vinblastine
Brand: Vincristine Injection
Generic: vincristine
Brand: Navelbine
Generic: vinorelbine
Vinca Alkaloids Warning Labels
- REFRIGERATE; DO NOT FREEZE (vinorelbine)
- AVOID ASPIRIN AND NSAIDS
- EXERCISE PRECAUTIONS FOR HANDLING, PREPARING, AND ADMINISTERING
- FATAL IF GIVEN INTRATHECALLY. FOR IV USE ONLY.
Anthracyclines Examples
- doxorubicin
- daunorubicin
- epirubicin
- idarubicin
- mitoxantrone
Brand:
- Adriamycin PFS
- Caelyx
- Myocet
Generic: doxorubicin
Brand: Cerubidine
Generic: daunorubicin
Brand: Pharmorubicin PFS
Generic: epirubicin
Brand: Idamycin
Generic: idarubicin
Brand: Mitoxantrone Injection
Generic: mitoxantrone
Anthracyclines Warning Labels
- AVOID PREGNANCY
- PROTECT FROM LIGHT
- MAY CAUSE DISCOLORATION OF URINE
- EXERCIZE PRECAUTIONS FOR HANDLING
Topoisomerase Inhibitors Examples
- etoposide
- teniposide
- irinotecan
- topotecan
Brand: Vepesid
Generic: etoposide
Brand: Camptosar
Generic: irinotecan
Brand: Vumon
Generic: teniposide
Brand: Hycamtin
Generic: topotecan
Topoisomerase Inhibtors Warning Labels
-EXERCISE PRECAUTIONS FOR HANDLING, PREPARING AND ADMINISTERING
Platinum Compounds Examples
- carboplatin
- cisplatin
- oxaliplatin
Brand: Paraplatin
Generic: carboplatin
Brand: Cisplatin
Generic: cisplatin
Brand: Eloxatin
Generic: oxaliplatin
Platinum Compounds Warning Labels
- EXERCISE PRECAUTIONS FOR HANDLING
- PROTECT FROM LIGHT (cisplatin)
Fluoropyrimidines Examples
- capecitabine
- cytarabine
- fludarabine
- fluorouracil
- gemcitabine
Brand: Xeloda
Generic: capecitabine
Brand: Cytosar
Generic: cytarabine
Brand: Fludara
Generic: fludarabine
Brand:
- Efudex
- 5-FU
Generic: fluorouracil
Brand: Gemzar
Generic: gemcitabine
Fluoropyrimidines Warning Labels
- EXERCISE PRECAUTIONS (5-FU, cytarabine, fludarabine, gemcitabine)
- AVOID PREGNANCY (5-FU, capecitabine)
- AVOID PROLONGUED EXPOSURE TO SUNGLIGHT (5-FU)
- ROOM TEMP (gemcitabine)
Antimetabolites Examples
- methotrexate
- mercaptopurine
- thioguanine
Brand: Methotrexate
Generic: methotrexate
Brand: Purinethol
Generic: mercaptopurine
Brand: Lanvis
Generic: thioguanine
Antimetabolites Warning Labels
- DO NOT DRINK ALCOHOL
- AVOID PROLONGUED EXPOSURE TO SUNLIGHT
- AVOID PREGNANCY
- EXERCISE PRECAUTIONS FOR HANDLING ETC.
- AVOID ASPIRINS AND NSAIDS (mercaptopurine)
Misc. Cancer Drugs
- bleomycin
- dactinomycin
- hydroxyurea
Brand: Blenoxane
Generic: bleomycin
Brand: Cosmegan
Generic: dactinomycin
Brand: Hydrea
Generic: hydroxyurea
Monoclonal Antibodies Examples
- bevacizumab
- trastuzumab
Brand: Avastin
Generic: bevacizumab
Brand: Herceptin
Generic: trastuzumab
Kinase Inhibitor Example
-imatinib
Brand: Gleevec
Generic: imatinib