Viruses/Fungi 3 Flashcards

1
Q

HSV-1: incidence

A

~70% over 12 harbor HSV-1

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2
Q

HSV-1 is responsible for

A

cold sores

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3
Q

How can HSV be transmitted to genitals?

A

oral sex

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4
Q

local s/s of HSV-1:

A

vesicles and ulcers on:

  • mouth
  • throat
  • lips
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5
Q

possible ystemic s/s of HSV-1:

A
  • fever
  • myalgias
  • malaise
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6
Q

timeframe for sx resolution of HSV-1:

A

3-14 days

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7
Q

recurrence of HSV-1

A

usually milder

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8
Q

HSV-2 is responsible for:

A
  • genital ulcers

- genital herpes

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9
Q

How many people have HSV-2?

A

more than 50 million

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10
Q

HSV-2 and HIV

A

HSV-2 increases the risk of acquiring HIV at least 2x!

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11
Q

s/s of HSV-2: vesicles and lesions on cutaneous surfaces of:

A
  • genitals
  • cervix
  • buttocks
  • bladder
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12
Q

lesion characteristics: HSV-2

A
  • painful
  • small
  • grouped
  • burning
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13
Q

timeframe for healing of HSV-2 lesions

A

1-3 weeks

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14
Q

systemic s/s with HSV-2?

A

possibly

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15
Q

reactivation of HSV-2 associated with

A

prodrome

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16
Q

prodrome

A

tingling or pain

17
Q

varicella-zoster responsible for

A
  • chickenpox

- shingles

18
Q

varicella-zoster primary infection

A

chickenpox

19
Q

varicella-zoster secondary infection

A

shingles

20
Q

ratio of people who will develop shingles after having chickenpox

A

1 in 3

21
Q

Where does varicella-zoster often persist in the body?

A

dorsal root ganglia

22
Q

How is varicella-zoster acquired?

A

airborne droplets

23
Q

varicella-zoster activity

A
  • multiplies at site of entry

- spreads to bloodstream

24
Q

How long does varicella-zoster take to spread to bloodstream?

A

4-6 days

25
Q

Incubation period for varicella-zoster

A

14-16 days from exposure

26
Q

When does is varicella-zoster contagious?

A
  • 1-2 days prior to demo of tx

- maintains contagiousness until lesions have crusted

27
Q

How is shingles different from chickenpox?

A

eruptions follow dermatome distribution

28
Q

PHN

A

post-herpetic neuralgia

29
Q

PHN is associated with this, and may last a lifetime

A

shingles

30
Q

What can happen with PHN?

A
  • pain
  • hyperalgesia
  • allodynia
31
Q

hyperalgesia

A

increased pain from a painful stimulus

32
Q

allodynia

A

painful rxn to nonpainful stimulus

33
Q

What is herpes-zoster ophthalmicus?

A
  • medical emergency

- VZV near the eye that needs eval by ophthalmologist

34
Q

What increases risk of shingles?

A
  • over 50

- immunocompromised

35
Q

causes of shingles

A
  • multifactorial

- related to cell-mediated immunity