9.21 Injury, Inflammation, Healing 6

Question 1

What is the general term for WBCs?

Answer 1

leukocytes

Question 2

What is the pneumonic for the types of leukocytes?

Answer 2

Never
Let
Monkeys
Eat
Bananas

Question 3

What does Never Let Monkeys Eat Bananas stand for?

types of leukocytes

Answer 3

• Neutrophils
• Lymphocytes
• Monocytes
• Eosinophils
• Basophils

Question 4

What are neutrophils?

Answer 4

the predominant phagocytes in the early inflammatory process

Question 5

When do neutrophils arrive on the scene?

Answer 5

6-12 hours after initial injury

first on the job

Question 6

neutrophils and cell division/lifespan

Answer 6

• incapable of cell division

- short lived

Question 7

What happens to neutrophils when they die?

Answer 7

• become part of exudate/pus

- removed from body

Question 8

What are the primary roles of neutrophils?

Answer 8

• remove debris and dead cells from sterile lesions

- phagocytosis of bacteria in nonsterile lesions

Question 9

What do lymphocytes mature into?

Answer 9

• T cells
• B cells
• plasma cells

Question 10

Lymphocytes are important in _____

Answer 10

immunity

Question 11

Concentrations of lymphocytes

Answer 11

Won’t see in large concentrations unless there’s something like leukemia going on

Question 12

Which are the largest of the normal blood cells?

Answer 12

monocytes

Question 13

Monocytes are produced here

Answer 13

bone marrow

Question 14

After entry into the _______, monocytes enter _______ to develop into ________

Answer 14

• inflammatory site
• circulation
• macrophages

Question 15

Monocytes replace _______ 24 hours after injury

Answer 15

neutrophils

Question 16

Monocytes are useful for this

Answer 16

long term defense

Question 17

Monocytes are seen in higher proportions in ___________

Answer 17

chronic inflammation

Question 18

Body’s primary defense against parasites

Answer 18

eosinophils

Question 19

How do eosinophils act?

Answer 19

• mildly phagocytic
• help regulate vascular mediators released by mast cels
• helps to limit inflammation

Question 20

What are basophils?

Answer 20

• mobile mast cells

- release similar inflammatory agent to eosinophils (?)

Question 21

Characteristics of chronic inflammation

Answer 21

• dense infiltration of lymphocytes and macrophages
• granuloma formation
• epithelioid cell formation
• giant cell formation

Question 22

Components of the inflammatory rxn

Answer 22

• vascular alterations
• leukocyte accumulations
• chemical mediation of inflammation
• phagocytosis