MS 1

Question 1

MS is the most common _____________

Answer 1

inflammatory demyelinating disease of the CNS

Question 2

What nerves does MS spare?

Answer 2

peripheral

Question 3

Inflammatory/demyelinating lesions form these

Answer 3

scars/plaques

Question 4

Where are demyelinating scars/plaques from MS found?

Answer 4

CNS white matter

Question 5

MS is characterized by these phases

Answer 5

• exacerbations

- remissions

Question 6

When do s/s of MS begin occurring?

Answer 6

• between 20-40

- peak at age 30

Question 7

Rare onset of MS occurs when?

Answer 7

• childhood

- after 50

Question 8

Women/Men are 2x as likely to get MS

Answer 8

Women

Question 9

What increases the likelihood of MS 10-fold?

Answer 9

family hx

Question 10

Is there an environmental component to MS?

Answer 10

yes - more prevalent in colder climates

Question 11

What are the types of MS?

Answer 11

• Clinically isolated syndrome (CIS)
• Relapsing-Remitting (RRMS)
• Primary Progressive (PPMS)
• Secondary Progressive (SPMS)

Question 12

What is CIS?

Answer 12

• FIRST episode of neuro sx due to demyelination of CNS

- MUST last at least 24 hours

Question 13

How is CIS different from MS?

Answer 13

Characteristic of MS but does not yet meet criteria for dx

Question 14

What must happen for it to be categorized as MS?

Answer 14

MUST have 2 separate documented lesions or episodes

Question 15

What is the most common type of MS?

Answer 15

Relapsing-Remitting (RRMS)

Question 16

What percentage of pts have RRMS?

Answer 16

85%

Question 17

What is RRMS?

Answer 17

• Periods of clearly defined exacerbations followed by period of remission
• Function returns to baseline/near baseline

Question 18

What is Primary Progressive MS?

Answer 18

Worsening function from onset of sx

Question 19

What is secondary progressive MS?

Answer 19

Follows an initial RRMS course