Study Guide 6 Flashcards

1
Q

What are the diagnostic tools for CNS disorders?

A
  • Clinical exam
  • CT
  • MRI T1
  • MRI T2
  • Functional MRI
  • PET scan
  • EEG
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2
Q

Why would a CT be chosen over an MRI?

A
  • faster than MRI
  • better for bone, chest, abdomen, spine, pelvis, tumors
  • better dx of hemorrhagic vs. occlusive CVA

FAST

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3
Q

CT uses:

A

Radiation

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4
Q

Both types of MRIs use:

A

Magnets and radio waves

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5
Q

How long do MRIs take?

A

30 mins

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6
Q

What are MRIs best for visualizing?

A
  • soft tissue
  • tendons
  • joints
  • ligaments
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7
Q

Types of MRI are different with this

A

Relaxation time

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8
Q

MRI T1 uses (relaxation time)

A

Longitudinal relaxation time

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9
Q

MRI T2 uses (relaxation time)

A

Transverse relaxation time

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10
Q

Which MRI is used with gadolinium contrast?

A

MRI T1

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11
Q

What does gadolinium contrast allow with an MRI T1?

A
  • see vascular changes
  • normal vessels
  • disruption of BBB
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12
Q

Transverse relaxation time (T2) is good for:

A
  • brain anatomy
  • CSF spaces
  • most brain lesions
  • early hemorrhage
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13
Q

What does a functional MRI depend upon?

A

Blood oxygenation level

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14
Q

What does a functional MRI look at?

A
  • functional activation of brain during tasks
  • can be used in research
  • track changes in ability to perform motor, visual, cognitive tasks
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15
Q

What does a PET scan visualize?

A

cellular activity via regional blood flow

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16
Q

PET scan is good for:

A
  • organ function study
  • regional density of some NTs
  • can be used to look at functional brain activation
17
Q

What does EEG look at?

A

Amplitude of transmissions

18
Q

EEG is used to assess

A
  • hearing
  • coma functioning
  • brainstem function

Brainstem auditory evoked potential

19
Q

What does this look like: CSF, T1-weighted

A

Dark

20
Q

What does this look like: CSF, T2-weighted

A

Bright

21
Q

What does this look like: white matter, T1

A

Light

22
Q

What does this look like: white matter, T2

A

Dark gray

23
Q

What does this look like: cortex, T1

A

Gray

24
Q

What does this look like: cortex, T2

A

Light gray

25
Q

What does this look like: fat, T1

A

Bright

26
Q

What does this look like: fat, T2

A

Light

27
Q

What does this look like: inflammation, T1

A

Dark

28
Q

What does this look like: inflammation, T2

A

Bright

29
Q

What are the goals of pharmacological control of CNS damage/disorder?

A
  • change production and uptake of NT
  • selective interaction with NT receptors
  • modulation of synthesis, release, reuptake, and degradation of NTs
  • mediation of NT release by action at presynaptic receptors