9.19 Injury, Inflammation, Healing 2 Flashcards
Both acute and chronic cell injury can be
reversible
impaired cell function and ion content for an acute reversible injury with sublethal stimulus
- increased ion content (Na+ and Ca2+)
- cell swells due to fluid retention
blebs
plasma membrane seals off and detaches
If this survives, the cell can recover
nucleus
What are the typical ways a cell adapts?
- atrophy
- hypertrophy
- hyperplasia
- metaplasia
- dysplasia
Chronic adaptation allows the body to
survive in an altered environment and avoid injury
What do intracellular accumulations do?
alter cell function
What types of things can accumulate in cells?
- lipids
- proteins
- carbs
- pigment
example of an intracellular accumulation
hepatocytes
hepatocytes are often seen in
fatty liver with alcohol abuse
Irreversible injury leads to
cell death
apoptosis
programmed cell death
necrosis
end point of degradation of cells
What are the 3 types of necrosis?
- dry gangrene
- wet gangrene
- gas gangrene
dry gangrene
- bacterial infection
- ischemia
