Misc Leftover Info Flashcards
Common goal for anti-seizure meds
Suppress excitability of neurons that are causing seizures
Many anti-seizure drugs are sedating, especially these
First generation
Most anti-seizure drugs have these sedating side effects
- sleepiness
- fatigue
- lethargy
Which drug is often used to stop severe, uncontrolled seizures
Nembutal
when other drugs are ineffective
Which anti-seizure meds are also used to treat bipolar disorder?
Valproates
Why are second gen drugs generally more favorable?
Better
- absorption
- distribution
- metabolism
Anti-seizure meds: therapy scheduling
Should be about an hour after a dose
Pregnancy precautions for anti-seizure meds
Risks of congenital malformations increased
Withdrawal from anti-seizure meds: seizure free afterwards
60-70% can be free of seizures after meds withdrawn
Criteria for withdrawing from seizure meds
- free of seizures for at least 2 years on meds
- good control of seizures within first year after seizures start
- normal neuro exam prior to withdrawal
- initial onset of seizures during childhood
How should a pt be taken off seizure meds?
Tapered off over 3-6 months
Special concerns for rehab pts who have seizures
- maintaining drug dosage within therapeutic window
- understand that seizures can be triggered by environmental factors
Why do you get a drug hangover the next day?
Drugs are lipid soluble and stay in the system for longer
Barbiturates are mostly used in _______ situations
Controlled
