Ciccone Doc 2

Question 1

Act on membrane synthesis

Answer 1

• penicillins
• cephalosporins
• carbapenems

Question 2

Side effects of penicillins

Answer 2

skin rxns

Question 3

What are the skin rxns that can happen from penicillins?

Answer 3

• Stephens-Johnson syndrome

- Toxic epidermal necrolysis

Question 4

Toxic epidermal necrolysis is (non-life threatening/life threatening)

Answer 4

life threatening

Question 5

Stephens-Johnson syndrome

Answer 5

painful rash followed by blisters

Question 6

Prolonged use of penicillins can cause

Answer 6

CNS issues

Question 7

CNS issues from penicillin long term use

Answer 7

• hallucinations
• confusion
• hemolytic anemia
• thrombocytopenia

Question 8

Penicillins have cross-sensitivity with

Answer 8

cephalosporins

Question 9

Cephalosporins work on the same bugs as

Answer 9

penicillins

Question 10

These are better for UTIs than penicillins

Answer 10

cephalosporins

Question 11

Cephalosporins are used _______, often seen with _____ patients

Answer 11

• prophylactically

- SCI

Question 12

These antibiotics that work on membrane synthesis can cause CNS abnormalities

Answer 12

carbapenems

Question 13

Who is vulnerable to CNS abnormalities caused by carbapenems?

Answer 13

• pre-existing seizure disorder

- drug dosage too high

Question 14

Example of a topical drug that acts on cell wall synthesis

Answer 14

Bacitracin

Question 15

Side effect of Bacitracin

Answer 15

local hypersensitivity

Question 16

Side effects of Vancomycin

Answer 16

• bitter taste in mouth
• nephrotoxicity
• ototoxicity
• red man rash from vancomycin load
• hypersensitivity