Viruses/Fungi 2 Flashcards
Viruses tend to become:
- latent
- chronic
- recurrent
How many types of herpesviruses?
8
How are herpesviruses similar/different?
- morphologically similar
- distinct biologic factors
This is more common than symptomatic illness with herpesviruses
subclinical primary infection
How long do the herpesviruses stay with the host?
Each type persists in a latent state for the life span of the host
Herpesviruses can be severe/fatal in these groups due to opportunistic infection
- infants
- immunocompromised
Type 1
HSV-1
Type 2
HSV-2
Type 3
Varicella-zoster
Type 4
Epstein-Barr infectious mononucleosis (EBV)
Type 5
Cytomegalovirus (CMV)
Type 6
Roseola human herpes virus (HHV)
Type 7
Herpes serologically associated with roseola (HHV)
Type 8
Human herpes associated with Kaposi’s sarcoma (HHV)
HSV-1, HSV-2 infect here
- any organ
- mucocutaneous site
With HSV-1 and 2, what triggers reactivation of the latent virus?
- physical stress
- psychological stress
What are some of the other infections that occur with HSV-1 and 2?
- viral meningitis
- herpes encephalitis
- fetus acquisition of HSV
- herpetic keratitis
- herpetic whitlows
- disseminate to visceral organs
viral meningitis
inflammation of meninges surrounding the brain
herpes encephalitis
- infection of brain tissue
- rare
fetus acquisition of HSV
- 50% probability
- can be fatal if untreated
What reduces the risk of fetus acquisition of HSV?
c-section
What is herpetic keratitis?
- ulceration of the cornea from infection
- common cause of corneal blindness
