9.21 Injury, Inflammation, Healing 7 Flashcards
1
Q
steps of vascular alterations after injury
A
- initial vasoconstriction
- vasodilation
- clot formation (if vessel disruption)
- transudation (if vessel not disrupted)
2
Q
initial vasoconstriction
A
- chemically mediated
- 5-10 mins after injury
3
Q
Initial vasoconstriction is chemically mediated by this hormone
A
norepinephrine
4
Q
Why does the body undergo initial vasoconstriction?
A
to stop bleeding
5
Q
vasodilation is chemically mediated by these
A
- histamine
- Hageman factor
- bradykinin
- prostaglandins
- complement fractions
6
Q
When does vasodilation occur?
A
- after initial vasoconstriction
- 1 hour after injury
7
Q
If the vessel is disrupted, what happens after vasodilation?
A
aggregation of platelets forms a clot
8
Q
Transudation: vessel not disrupted
A
- NEURALLY mediated arterial constriction is followed by vasodilation
- protein-poor fluid forced into injured tissue
9
Q
transudate composition
A
- dissolved electrolytes
- water
10
Q
exudate composition
A
- plasma proteins
- lipids
- cellular debris (cloudy)
11
Q
pus composition
A
- neutrophils
- digested tissue
- fluid
- bacteria
12
Q
What are the types of transudate?
A
- transudate
- exudate
- pus
- blood
- effusion
13
Q
What is effusion?
A
swelling within a cavity
14
Q
types of effusion
A
- joint effusion
- pleural effusion
- ascites
- peritoneal effusion
15
Q
ascites
A
abdominal effusion
