Vecuronium Flashcards
Vecuronium Trade Name?
Vecuronium (Norcuron)
(Not carried by Nuvance)
Vecuronium Classification?
Nondepolarizing neuromuscular blocker, cholinergic receptor antagonist, paralytic agent
Vecuronium Mechanism?
Capital: Binds competitively to cholinergic receptors at the motor end plate to antagonize the action of acetylcholine producing skeletal muscle paralysis without effecting consciousness
StatPearls: Vecuronium is a nondepolarizing agent that achieves skeletal muscle paralysis by competing with acetylcholine for cholinergic receptor sites and binding with the nicotinic cholinergic receptor at the postjunctional membrane of the motor endplate, producing muscle paralysis without effecting consciousness.
Vecuronium Indications?
Paralytic agent used as a component of RSI
Vecuronium Contraindications?
Hypersensitivity and anticipated difficult/ failed airway, hepatic or renal disease. Avoid using on patients with chronic neuromuscular disease (e.g. muscular dystrophy)
Vecuronium Side Effects/Precautions?
Bronchospasm (rare), Hypotension,
Does not stop neuronal seizure activity
Although after administering this neuromuscular blocking drug it may appear that the patient is not conscious, it has NO effect on the central nervous system, so the patient will be completely aware of procedures unless appropriate sedation is also given
Vecuronium Adult Dose?
CT Protocols: 0.1 mg/kg IV/IO
Vecuronium Pediatric Dose?
CT Protocols: 0.1 mg/kg IV/IO (same)
Vecuronium Onset of Action?
Medscape: 3-5 minutes
Vecuronium Duration of Action?
Medscape: 20-35 minutes
Vecuronium Max Dose Adult/Pediatric?
None stated
Vecuronium Routes of Administration?
IV/IO
Vecuronium How Supplied?
10mg and 20mg vials requiring reconstitution
