Etomidate

Question 1

Etomidate Trade Name?

Answer 1

Amidate

Question 2

Etomidate Classfication?

Answer 2

General anesthetic, non-barbiturate sedative hypnotic

Question 3

Etomidate Mechanism?

Answer 3

Capital: Etomidate binds with GABA receptors causing an influx of chloride into the post-synaptic neuron to hyperpolarize it and slow conduction.

Question 4

Etomidate Indications?

Answer 4

Premedication prior to procedures such as RSI, endotracheal intubation, synchronized cardioversion, conscious sedation for bone dislocation relocation.

Question 5

Etomidate Contraindications?

Answer 5

Hypersensitivity, labor and delivery

Question 6

Etomidate Side Effects/Precautions?

Answer 6

Hypotension, hypertension, dysrhythmia, hypoventilation, nausea/ vomiting, cortisol suppression, hypersensitivity, pain at injection site

May suppress adrenal gland production of steroid hormones, which can cause temporary gland failure. Avoid routine use in patients with long term sympathetic output (sepsis)

Question 7

Etomidate Adult Dose?

Answer 7

0.3mg/kg IV over 30-60 sec, limited to one dose

Question 8

Etomidate Pediatric Dose?

Answer 8

PALS:
0.2 to 0.4 mg/kg IV/IO infused over 30 to 60 seconds (max 20mg) will produce rapid sedation that lasts for 10-15 mins

Capital:
>10 years- 0.3mg/kg IV over 30-60 sec with a max dose of 20 mg

Question 9

Etomidate Onset of Action?

Answer 9

< 1 minute

Question 10

Etomidate Duration of Action?

Answer 10

3-5 mins

Question 11

Etomidate Max Dose Adult/Pediatric?

Answer 11

Adult limit 1 dose (Pediatric 20mg)

Question 12

Etomidate Routes of Administration?

Answer 12

IV/IO over 30-60 sec

Question 13

Etomidate How Supplied?

Answer 13

20mg/10ml (2mg/ml) vials
“In the field, 20 Etomidate, 200 Succ”