Dopamine Flashcards
Dopamine Trade Name
Intropin
(In CT Protocols for Pedi only)
(Not Carried by Nuvance)
Dopamine Classification
Medscape: Inotropic Agent, Sympathomimetic
Dopamine Mechanism
Medscape:
Endogenous catecholamine, acting on both dopaminergic and adrenergic neurons.
Low dose stimulates mainly dopaminergic receptors, producing renal and mesenteric vasodilation; higher dose stimulates both beta1-adrenergic and dopaminergic receptors, producing cardiac stimulation and renal vasodilation; large dose stimulates alpha-adrenergic receptors.
Capital:
Binds to dopaminergic, Alpha 1, and Beta 1 adrenergic receptors in a dose-dependent fashion to increase blood pressure by increasing inotropy, chronotropy, dromotropy and peripheral vascular resistance.
Dopamine Onset of Action
Capital: 1-4 Minutes
Dopamine Duration of Action
Capital: Effects cease immediately after discontinuation of infusion
Dopamine Indications
Capital:
Non-hypovolemic shock, Symptomatic bradycardia
Dopamine Contraindications
Capital:
Hypovolemia, Tachydysrhythmia
Dopamine Side Effects/ Precautions/ Comments
Capital:
Tachycardia, Hypertension, Increased myocardial oxygen demand, Dysrhythmia, Headache, Nausea/vomiting, Syncope
Incompatible with sodium bicarbonate and furosemide
β-blockers may blunt effects
Monitor blood pressure closely, May increase infarct size in patients having AMI, Correct hypovolemia before administering
Dopamine Adult Dose
Capital:
For dopaminergic effects: 2-5 mcg/kg/min IV/IO infusion
For Beta1 effect: 5-10 mcg/kg/min IV/IO infusion
For Alpha1 effect: 10-20 mcg/kg/min IV/IO infusion
Dopamine Pediatric Dose
Capital:
Same as adult
Dopamine
Max Dose Adult (Pediatric)
??
Dopamine Routes of Administration
IV/IO
Dopamine How Supplied
400mg vials, premixed solution, Mix 400mg in 250ml NS for a concentration of 1600 mcg/ml
