Succinylcholine Flashcards
Succinylcholine Trade Name?
(Anectine, suxamethonium, Quelicin)
(Not carried by Danbury)
Succinylcholine Classification?
Depolarizing neuromuscular blocker
Succinylcholine Mechanism?
Capital/Medscape/Statpearls:
Succinylcholine is a short acting, depolarizing neuromuscular blocking agent that binds to acetylcholine receptor sites. This produces fasciculation and muscular contractions. After this contraction, the acetylcholine can still not bind and no further contractions can occur, causing muscle relaxation or “paralysis”. It is the only depolarizing blocker in use today and is ideal due to its short onset and duration.
Succinylcholine Indications?
CT Protocols:
Paralytic agent used as a component of RSI.
Succinylcholine Contraindications?
CT Protocols:
Hypersensitivity and anticipated difficult/ failed airway, chronic neuromuscular conditions (myasthenia gravis).
Avoid in patients with burns > 24 hrs old, chronic neuromuscular disease (eg muscular dystrophy), ESRD, or other situation in which hyperkalemia is likely
Succinylcholine Side Effects/Precautions?
Capital: Hyperkalemia, Malignant hyperthermia, Salivation, Dysrhythmia, Fasciculations, Prolonged muscle rigidity, Rhabdomyolysis, Kidney injury
Although after administering Succinylcholine it may appear that the patient is not conscious, it has NO effect on the central nervous system, so the patient will be completely aware of procedures unless appropriate sedation is also given
Succinylcholine Adult Dose?
CT Protocols:
1.5 mg/kg IV/IO immediately after sedation (maximum 200 mg)
Succinylcholine Pediatric Dose?
1 mg/kg IV/IO immediately after sedation (maximum 75 mg)
Succinylcholine Onset of Action?
Medscape: 30-60 sec (IV); 2-3 min (IM)
Succinylcholine Duration of Action?
Medscape: Duration: 4-6 min (IV); 10-30 min (IM)
Succinylcholine Max Dose Adult/Pediatric?
200mg (75mg)
Succinylcholine Routes of Administration?
IV/IO
Succinylcholine How Supplied?
200mg/10ml vials and prefilled syringes
