Atropine Flashcards
Atropine Trade Name
Atreza, Atropine PO, SalTropine
Atropine Classification
Medscape:
Anticholinergic, Antispasmodic Agents
Capital:
Parasympatholytic/Anticholinergic
(Parasympathetic Antagonist)
Atropine Mechanism
Medscape:
Antimuscarinic; inhibits action of acetylcholine at parasympathetic sites in smooth muscle, CNS, and secretory glands. Increases cardiac output and dries secretions
Capital:
Inhibits the actions of acetylcholine to block parasympathetic stimulation
Atropine Onset of Action
PALS: Rapid
Atropine Duration of Action
Medscape:
Duration: 4 hr
Atropine Indications
CT Protocols:
Bradycardia, Organophosphate poisoning, Cholinergic nerve agent exposure,
RSI premedication
Capital:
Symptomatic bradycardia, Organophosphate/nerve agent poisoning
Atropine Contraindications
CT Protocols:
Allergy: Cease administration if atropine toxicity is observed (tachycardia, dry/hot skin, etc.)
Capital:
Tachycardia, Hypersensitivity, Hypothermic bradicardia, Relatively contraindicated in STEMI
Atropine Side Effects/ Precautions/ Comments
Capital:
Tachycardia, Palpitations, Dysrhythmia, Dry mouth, Increased myocardial oxygen demand, Nausea/vomiting, Pupillary dilation
Atropine Adult Dose
CT Protocols:
Bradycardia
1.0 mg IV/IO every 3 – 5 minutes up to maximum of 3mg.
Organophosphate Poisoning and Nerve Agent
2 mg IM or IV/IO; double dose and repeat every 5 minutes
(i.e. 4mg, then 8mg, etc.) until out of atropine or bronchorrhea ceases.
Rapid Sequence Intubation
Consider 0.5mg IV/IO for bradycardia
Atropine Pediatric Dose
Capital:
Bradycardia: 0.02 mg/kg (minimum 0.1 mg, max 1 mg). May repeat once.
Atropine
Max Dose Adult (Pediatric)
3mg (1mg)
Atropine Routes of Administration
IV/IO
Atropine How Supplied
Atropine Sulfate 1mg/10ml syringe
