Hydromorphone

Question 1

Hydromorphone Trade Name

Answer 1

(Dilaudid) (Not carried by Danbury)

Question 2

Hydromorphone Classification

Answer 2

CT Protocols:
Opioid analgesic

Question 3

Hydromorphone Mechanism

Answer 3

Medscape:
Mu-opioid receptor agonist; inhibits ascending pain pathways, thus altering response to pain; main therapeutic action is analgesia. Other pharmacologic effects include respiratory depression and sedation; suppresses cough by acting centrally in medulla

Capital:
Binds to opiate receptors in central nervous system to cause analgesia and euphoria.
New Britain:
Opioid R agonist, causes hyperpolarization of the interneurons and decreased release of neurotransmitters responsible to transmission of pain impulses to the thalamus and cerebral cortex

Question 4

Hydromorphone Onset of Action

Answer 4

Medscape:
5 min (IV), 15-30 min (PO, SC, IM)

Question 5

Hydromorphone Duration of Action

Answer 5

Medscape:
3-4 hr (PO/IV)

Question 6

Hydromorphone Indications

Answer 6

CT Protocols:
Moderate to severe pain
Post intubation analgesia

Question 7

Hydromorphone Contraindications

Answer 7

CT Protocols:
Allergy, Respiratory depression or insufficiency, Uncorrected hypotension

Question 8

Hydromorphone Side Effects/ Precautions/ Comments

Answer 8

Capital:
Respiratory depression, Confusion, Sedation, Bradycardia, Hypotension, Nausea/vomiting, Tachycardia, Syncope

Question 9

Hydromorphone Adult Dose

Answer 9

CT Protocols:
0.5-1 mg IV/IO, every 5 minutes to a total 4 mg titrated to
pain relief

Question 10

Hydromorphone Pediatric Dose

Answer 10

CT Protocols:
Not listed
Capital:
0.015 mg/kg IV/IO/IM

Question 11

Hydromorphone Max Dose Adult (Pediatric)

Answer 11

4mg

Question 12

Hydromorphone Routes of Administration

Answer 12

IV/IO/IM, PO

Question 13

Hydromorphone How Supplied

Answer 13

1 mg and 2 mg vials