Dobutamine

Question 1

Dobutamine Trade Name

Answer 1

Dobutrex
(Not in CT Protocols)
(Not Carried by Nuvance)

Question 2

Dobutamine Classification

Answer 2

Medscape: Inotropic Agent, Sympathomimetic

Question 3

Dobutamine Mechanism

Answer 3

Medscape:
Strong beta1 and weak beta2/alpha effects, resulting in increased cardiac output, blood pressure, and heart rate, as well as decreased peripheral vascular resistance

Capital:
Binds to β-1 adrenergic receptors to increase inotropic force with little effect on chronotropy

Question 4

Dobutamine Onset of Action

Answer 4

Capital: 2 Minutes

Question 5

Dobutamine Duration of Action

Answer 5

Capital: 1-2 minutes after discontinuation of infusion

Question 6

Dobutamine Indications

Answer 6

Capital:
Cardiogenic shock, CHF

Question 7

Dobutamine Contraindications

Answer 7

Capital:
Hypersensitivity, Tachydysrhythmia, Bradycardia, Hypovolemia

Question 8

Dobutamine Side Effects/ Precautions/ Comments

Answer 8

Capital:
Tachycardia, Hypertension, Increased myocardial oxygen demand, Dysrhythmia, Headache, Nausea/vomiting, Syncope

Incompatible with sodium bicarbonate and furosemide
β-blockers may blunt effects

Monitor blood pressure closely, May increase infarct size in patients having AMI, Correct hypovolemia before administering

Question 9

Dobutamine Adult Dose

Answer 9

Capital:
2-20 mcg/kg/min IV/IO drip

Question 10

Dobutamine Pediatric Dose

Answer 10

Capital:
Same as adult
2-20 mcg/kg/min IV/IO drip

Question 11

Dobutamine
Max Dose Adult (Pediatric)

Answer 11

??

Question 12

Dobutamine Routes of Administration

Answer 12

IV/IO

Question 13

Dobutamine How Supplied

Answer 13

Mix 250mg in 250-500 ml NS for a concentration of 500-1000 mcg/ml