Ondansetron

Question 1

Ondansetron Trade Name

Answer 1

Zofran

Question 2

Ondansetron Classification

Answer 2

CT Protocols:
Antiemetic

Question 3

Ondansetron Mechanism

Answer 3

Medscape:
A selective 5-HT3-receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone

Has no effect on dopamine receptors and therefore does not cause extrapyramidal symptoms

Question 4

Ondansetron Onset of Action

Answer 4

Medscape:
30 Mins

Question 5

Ondansetron Duration of Action

Answer 5

Medscape:
3-6 hours

Question 6

Ondansetron Indications

Answer 6

CT Protocols:
Nausea and/or vomiting (anti-emetic)

Question 7

Ondansetron Contraindications

Answer 7

Capital:
Hypersensitivity

Question 8

Ondansetron Side Effects/ Precautions/ Comments

Answer 8

Capital:
Prolonged QT interval, Heart block, Headache, Constipation, Diarrhea, Dry mouth

Question 9

Ondansetron Adult Dose

Answer 9

CT Protocols
4 mg IV/IO/IM/PO

Question 10

Ondansetron Pediatric Dose

Answer 10

Fortin:
0.1 mg/kg (max 4mg) IV/IO/IM/PO

Question 11

Ondansetron Max Dose Adult (Pediatric)

Answer 11

(max 4mg for pedi)

Question 12

Ondansetron Routes of Administration

Answer 12

IV/IO/IM/PO

Question 13

Ondansetron How Supplied

Answer 13

4mg/2ml, 4mg tablet