Hydrocortisone Flashcards
Hydrocortisone Trade Name
(Solu-Cortef)
(Not carried by Danbury)
Hydrocortisone Classification
Medscape:
Corticosteroids
Capital:
Adrenal glucocorticoid
Hydrocortisone Mechanism
Medscape:
Glucocorticoid; elicits mild mineralocorticoid activity and moderate anti-inflammatory effects; controls or prevents inflammation by controlling rate of protein synthesis, suppressing migration of polymorphonuclear leukocytes (PMNs) and fibroblasts, and reversing capillary permeability
Capital:
Inhibits pro-inflammatory substances and synthesis of pro-inflammatory enzymes
Hydrocortisone Onset of Action
Capital: 1 hour
Hydrocortisone Duration of Action
Capital: 8-12 hours
Hydrocortisone Indications
Capital:
Shock due to adrenal insufficiency, Anaphylaxis, Asthma, COPD
CT Protocols:
Adrenal insufficiency
Hydrocortisone Contraindications
Capital:
Systemic fungal infection, Premature infants, Hypersensitivity
Hydrocortisone Side Effects/ Precautions/ Comments
Capital:
Headache, Vertigo, CHF, Hypertension, Fluid and salt retention, Nausea
Solu-Medrol preferred for reactive airway disease and anaphylaxis; Solu-Cortef preferred for adrenal insufficiency
Incompatible with heparin
Give to any pt with known adrenal insufficiency if they also have:
Shock, fever, trauma, drowning, hyper/hypothermia, long bone fractures, vomit/Diarrhea w/ dehydration, respiratory distress, 2nd or 3rd degree burns, RSI
Hydrocortisone Adult Dose
Capital:
4 mg/kg IV/IO
CT Protocols:
100mg IV/IO/IM
Hydrocortisone Pediatric Dose
Capital:
2 mg/kg IV/IO, max 100 mg
Hydrocortisone
Max Dose Adult (Pediatric)
(100mg)
Hydrocortisone Routes of Administration
IV/IO/IM
Hydrocortisone How Supplied
100 mg, 250 mg, and 500 mg powders with diluent provided for reconstitution
