Levalbuterol

Question 1

Levalbuterol Trade Name?

Answer 1

Xopenex (Not carried by Danbury)

Question 2

Levalbuterol Classification?

Answer 2

Sympathomimetic, Beta2 Agonist

Question 3

Levalbuterol Mechanism?

Answer 3

Medscape:
Albuterol is a 50:50 racemic mixture of (R)-albuterol (levalbuterol), the pharmacologically active enantiomer, and (S)-albuterol, which has little or no bronchodilating activity. Levabuterol “(R)-albuterol” demonstrates 100-fold more potent binding to beta-2 receptors than (S)-albuterol. Levalbuterol selectively binds to β-2 adrenergic receptors to cause smooth muscle relaxation in bronchioles, which in turn causes bronchodilation.

Question 4

Levalbuterol Indications?

Answer 4

CT Protocols: Asthma, COPD, Reactive Airway Disease
Capital: Bronchospasm

Question 5

Levalbuterol Contraindications?

Answer 5

Capital: Hypersensitivity, Tachydysrhythmia, relatively contraindicated in extreme tachycardia and hypertension

Question 6

Levalbuterol Side Effects/Precautions?

Answer 6

Capital: Headache, Tachycardia, Hypertension, Palpitations, Increased myocardial oxygen demand, Nausea/vomiting, Chest pain, Cough, Tremors, Dry mouth, Anxiety

Synergistic effect with other sympathomimetics,
β-blockers may blunt effects

Question 7

Levalbuterol Adult Dose?

Answer 7

CT Protocol: 1.25 mg via nebulizer, repeat every 20 minutes (4 doses total)

Capital: 0.63 mg in 3ml NS via nebulizer at 6-8 lpm oxygen

Question 8

Levalbuterol Pediatric Dose?

Answer 8

CT Protocol: 0.63 mg in 3ml NS via nebulizer at 6-8 lpm oxygen

Capital: 0.31 mg in 3ml NS via nebulizer at 6-8 lpm oxygen

Question 9

Levalbuterol Onset of Action?

Answer 9

Capital:
5-15 minutes

Question 10

Levalbuterol Duration of Action?

Answer 10

Capital:
6-8 hours

Question 11

Levalbuterol Max Dose Adult/Pediatric?

Answer 11

4 doses

Question 12

Levalbuterol Routes of Administration?

Answer 12

Nebulizer

Question 13

Levalbuterol How Supplied?

Answer 13

Capital:
0.63mg/3ml “bullets”