Racemic epinephrine

Question 1

Racemic epinephrine Trade Name?

Answer 1

(Vaponefrin, Micronefrin)

Question 2

Racemic epinephrine Classification?

Answer 2

Sympathomimetic, Beta2 Agonist

Question 3

Racemic epinephrine Mechanism?

Answer 3

Capital:
Chemical isomer of epinephrine that stimulates both a and b receptors with a slight preference for b2 to cause bronchodilation.
REMSA:
Racemic Epinephrine is an inhaled version of epinephrine that is used as a bronchodilator and as an anti-inflammatory to treat laryngeal/tracheal swelling and edema. Its actions are the same as epinephrine but since it is inhaled it has both systemic and localized effects.

Question 4

Racemic epinephrine Onset of Action?

Answer 4

Capital: 5 minutes

Question 5

Racemic epinephrine Duration of Action?

Answer 5

Capital: 1-3 hours

Question 6

Racemic epinephrine Indications?

Answer 6

CT Protocols: Bronchiolitis, Croup

Capital: Relieves subglottic edema associated with Croup and Laryngeal edema

Question 7

Racemic epinephrine Contraindications?

Answer 7

Capital: Hypersensitivity Hypertension, Epiglottitis, Significant cardiovascular disease

Question 8

Racemic epinephrine Side Effects/Precautions?

Answer 8

Capital: Tachycardia, Hypertension, Increased myocardial oxygen demand, Dysrhythmia, Headache, Nausea/vomiting, Syncope
Beta blockers may blunt effects

Question 9

Racemic epinephrine Adult Dose?

Answer 9

Capital: NA
CT Protocols: NA

Question 10

Racemic epinephrine Pediatric Dose?

Answer 10

CT Protocols
Nebulized racemic epinephrine 0.5 ml of 2.25% (11.25mg) w/ 3 mL 0.9% NaCl
OR Nebulized epinephrine, 5 mg of 1mg/ml (1:1,000). [* HIGH-RISK AGP*]

Question 11

Racemic epinephrine Max Dose Adult/Pediatric?

Answer 11

None found

Question 12

Racemic epinephrine Routes of Administration?

Answer 12

Nebulizer

Question 13

Racemic epinephrine How Supplied?

Answer 13

Capital:
2.25% solution